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Novel tricyclic glycal-based TRIB1 inducers that reprogram LDL metabolism in hepatic cells.
Nagiec MM, Duvall JR, Skepner AP, Howe EA, Bastien J, Comer E, Marie JC, Johnston SE, Negri J, Eichhorn M, Vantourout J, Clish C, Musunuru K, Foley M, Perez JR, Palmer MAJ. Nagiec MM, et al. Among authors: musunuru k. Medchemcomm. 2018 Sep 14;9(11):1831-1842. doi: 10.1039/c8md00297e. eCollection 2018 Nov 1. Medchemcomm. 2018. PMID: 30542533 Free PMC article.
Modulators of hepatic lipoprotein metabolism identified in a search for small-molecule inducers of tribbles pseudokinase 1 expression.
Nagiec MM, Skepner AP, Negri J, Eichhorn M, Kuperwasser N, Comer E, Muncipinto G, Subramanian A, Clish C, Musunuru K, Duvall JR, Foley M, Perez JR, Palmer MA. Nagiec MM, et al. Among authors: musunuru k. PLoS One. 2015 Mar 26;10(3):e0120295. doi: 10.1371/journal.pone.0120295. eCollection 2015. PLoS One. 2015. PMID: 25811180 Free PMC article.
EDEM3 Modulates Plasma Triglyceride Level through Its Regulation of LRP1 Expression.
Xu YX, Peloso GM, Nagai TH, Mizoguchi T, Deik A, Bullock K, Lin H, Musunuru K, Yang Q, Vasan RS, Gerszten RE, Clish CB, Rader D, Kathiresan S. Xu YX, et al. Among authors: musunuru k. iScience. 2020 Apr 24;23(4):100973. doi: 10.1016/j.isci.2020.100973. Epub 2020 Mar 11. iScience. 2020. PMID: 32213464 Free PMC article.
Programming human pluripotent stem cells into white and brown adipocytes.
Ahfeldt T, Schinzel RT, Lee YK, Hendrickson D, Kaplan A, Lum DH, Camahort R, Xia F, Shay J, Rhee EP, Clish CB, Deo RC, Shen T, Lau FH, Cowley A, Mowrer G, Al-Siddiqi H, Nahrendorf M, Musunuru K, Gerszten RE, Rinn JL, Cowan CA. Ahfeldt T, et al. Among authors: musunuru k. Nat Cell Biol. 2012 Jan 15;14(2):209-19. doi: 10.1038/ncb2411. Nat Cell Biol. 2012. PMID: 22246346 Free PMC article.
Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project.
Musunuru K, Romaine SP, Lettre G, Wilson JG, Volcik KA, Tsai MY, Taylor HA Jr, Schreiner PJ, Rotter JI, Rich SS, Redline S, Psaty BM, Papanicolaou GJ, Ordovas JM, Liu K, Krauss RM, Glazer NL, Gabriel SB, Fornage M, Cupples LA, Buxbaum SG, Boerwinkle E, Ballantyne CM, Kathiresan S, Rader DJ. Musunuru K, et al. PLoS One. 2012;7(5):e36473. doi: 10.1371/journal.pone.0036473. Epub 2012 May 21. PLoS One. 2012. PMID: 22629316 Free PMC article.
Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism.
Strong A, Ding Q, Edmondson AC, Millar JS, Sachs KV, Li X, Kumaravel A, Wang MY, Ai D, Guo L, Alexander ET, Nguyen D, Lund-Katz S, Phillips MC, Morales CR, Tall AR, Kathiresan S, Fisher EA, Musunuru K, Rader DJ. Strong A, et al. Among authors: musunuru k. J Clin Invest. 2012 Aug;122(8):2807-16. doi: 10.1172/JCI63563. Epub 2012 Jul 2. J Clin Invest. 2012. PMID: 22751103 Free PMC article.
Permanent alteration of PCSK9 with in vivo CRISPR-Cas9 genome editing.
Ding Q, Strong A, Patel KM, Ng SL, Gosis BS, Regan SN, Cowan CA, Rader DJ, Musunuru K. Ding Q, et al. Among authors: musunuru k. Circ Res. 2014 Aug 15;115(5):488-92. doi: 10.1161/CIRCRESAHA.115.304351. Epub 2014 Jun 10. Circ Res. 2014. PMID: 24916110 Free PMC article.
227 results