Chen YY - Search Results

1

The anticancer effects of MPT0G211, a novel HDAC6 inhibitor, combined with chemotherapeutic agents in human acute leukemia cells.

Tu HJ, Lin YJ, Chao MW, Sung TY, Wu YW, Chen YY, Lin MH, Liou JP, Pan SL, Yang CR. Tu HJ, et al. Among authors: chen yy. Clin Epigenetics. 2018 Dec 29;10(1):162. doi: 10.1186/s13148-018-0595-8. Clin Epigenetics. 2018. PMID: 30594243 Free PMC article.

2

A Novel Selective JAK2 Inhibitor Identified Using Pharmacological Interactions.

Lin TE, HuangFu WC, Chao MW, Sung TY, Chang CD, Chen YY, Hsieh JH, Tu HJ, Huang HL, Pan SL, Hsu KC. Lin TE, et al. Among authors: chen yy. Front Pharmacol. 2018 Dec 4;9:1379. doi: 10.3389/fphar.2018.01379. eCollection 2018. Front Pharmacol. 2018. PMID: 30564118 Free PMC article.

3

Combination treatment strategy for pancreatic cancer involving the novel HDAC inhibitor MPT0E028 with a MEK inhibitor beyond K-Ras status.

Chao MW, Chang LH, Tu HJ, Chang CD, Lai MJ, Chen YY, Liou JP, Teng CM, Pan SL. Chao MW, et al. Among authors: chen yy. Clin Epigenetics. 2019 May 29;11(1):85. doi: 10.1186/s13148-019-0681-6. Clin Epigenetics. 2019. PMID: 31142371 Free PMC article.

4

N-alkyl-hydroxybenzoyl anilide hydroxamates as dual inhibitors of HDAC and HSP90, downregulating IFN-γ induced PD-L1 expression.

Mehndiratta S, Lin MH, Wu YW, Chen CH, Wu TY, Chuang KH, Chao MW, Chen YY, Pan SL, Chen MC, Liou JP. Mehndiratta S, et al. Among authors: chen yy, chen ch, chen mc. Eur J Med Chem. 2020 Jan 1;185:111725. doi: 10.1016/j.ejmech.2019.111725. Epub 2019 Sep 24. Eur J Med Chem. 2020. PMID: 31655430

5

Synthesis and biological evaluation of acridine-based histone deacetylase inhibitors as multitarget agents against Alzheimer's disease.

Tseng HJ, Lin MH, Shiao YJ, Yang YC, Chu JC, Chen CY, Chen YY, Lin TE, Su CJ, Pan SL, Chen LC, Wang CY, Hsu KC, Huang WJ. Tseng HJ, et al. Among authors: chen yy, chen cy, chen lc. Eur J Med Chem. 2020 Apr 15;192:112193. doi: 10.1016/j.ejmech.2020.112193. Epub 2020 Feb 29. Eur J Med Chem. 2020. PMID: 32151835

6

Corrigendum to "N-alkyl-hydroxybenzoyl anilide hydroxamates as dual inhibitors of HDAC and HSP90, downregulating IFN-γ induced PD-L1 expression"[Eur. J. Med. Chem. 2020 Jan 1;185:111725].

Mehndiratta S, Lin MH, Wu YW, Chen CH, Wu TY, Chuang KH, Chao MW, Chen YY, Pan SL, Chen MC, Liou JP. Mehndiratta S, et al. Among authors: chen yy, chen ch, chen mc. Eur J Med Chem. 2020 Aug 1;199:112406. doi: 10.1016/j.ejmech.2020.112406. Epub 2020 May 11. Eur J Med Chem. 2020. PMID: 32408215 No abstract available.

7

A site-moiety map and virtual screening approach for discovery of novel 5-LOX inhibitors.

Hsu KC, HuangFu WC, Lin TE, Chao MW, Sung TY, Chen YY, Pan SL, Lee JC, Tzou SC, Sun CM, Yang JM. Hsu KC, et al. Among authors: chen yy. Sci Rep. 2020 Jun 29;10(1):10510. doi: 10.1038/s41598-020-67420-9. Sci Rep. 2020. PMID: 32601404 Free PMC article.

8

A novel histone deacetylase inhibitor MPT0L184 dysregulates cell-cycle checkpoints and initiates unscheduled mitotic signaling.

Chang TY, Nepali K, Chen YY, Yang YSH, Hsu KC, Yen Y, Pan SL, Liou JP, Lee SB. Chang TY, et al. Among authors: chen yy. Biomed Pharmacother. 2021 Jun;138:111485. doi: 10.1016/j.biopha.2021.111485. Epub 2021 Mar 16. Biomed Pharmacother. 2021. PMID: 33740521 Free article.

9

Identification of a dual FLT3 and MNK2 inhibitor for acute myeloid leukemia treatment using a structure-based virtual screening approach.

Yen SC, Chen LC, Huang HL, HuangFu WC, Chen YY, Eight Lin T, Lien ST, Tseng HJ, Sung TY, Hsieh JH, Huang WJ, Pan SL, Hsu KC. Yen SC, et al. Among authors: chen yy, chen lc. Bioorg Chem. 2022 Apr;121:105675. doi: 10.1016/j.bioorg.2022.105675. Epub 2022 Feb 11. Bioorg Chem. 2022. PMID: 35182882 Free article.

10

B-Cell ELISpot Assay to Quantify Antigen-Specific Antibody-Secreting Cells in Human Peripheral Blood Mononuclear Cells.

Hwai H, Chen YY, Tzeng SJ. Hwai H, et al. Among authors: chen yy. Methods Mol Biol. 2018;1808:133-141. doi: 10.1007/978-1-4939-8567-8_11. Methods Mol Biol. 2018. PMID: 29956179

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