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How complex should an in vitro model be? Evaluation of complex 3D alveolar model with transcriptomic data and computational biological network models.
Marescotti D, Serchi T, Luettich K, Xiang Y, Moschini E, Talikka M, Martin F, Baumer K, Dulize R, Peric D, Bornand D, Guedj E, Sewer A, Cambier S, Contal S, Chary A, Gutleb AC, Frentzel S, Ivanov NV, Peitsch MC, Hoeng J. Marescotti D, et al. Among authors: frentzel s. ALTEX. 2019;36(3):388-402. doi: 10.14573/altex.1811221. Epub 2019 Feb 12. ALTEX. 2019. PMID: 30753736 Free article.
In vitro systems toxicology approach to investigate the effects of repeated cigarette smoke exposure on human buccal and gingival organotypic epithelial tissue cultures.
Schlage WK, Iskandar AR, Kostadinova R, Xiang Y, Sewer A, Majeed S, Kuehn D, Frentzel S, Talikka M, Geertz M, Mathis C, Ivanov N, Hoeng J, Peitsch MC. Schlage WK, et al. Among authors: frentzel s. Toxicol Mech Methods. 2014 Oct;24(7):470-87. doi: 10.3109/15376516.2014.943441. Epub 2014 Sep 11. Toxicol Mech Methods. 2014. PMID: 25046638 Free PMC article.
Impact Assessment of Cigarette Smoke Exposure on Organotypic Bronchial Epithelial Tissue Cultures: A Comparison of Mono-Culture and Coculture Model Containing Fibroblasts.
Iskandar AR, Xiang Y, Frentzel S, Talikka M, Leroy P, Kuehn D, Guedj E, Martin F, Mathis C, Ivanov NV, Peitsch MC, Hoeng J. Iskandar AR, et al. Among authors: frentzel s. Toxicol Sci. 2015 Sep;147(1):207-21. doi: 10.1093/toxsci/kfv122. Epub 2015 Jun 16. Toxicol Sci. 2015. PMID: 26085348 Free PMC article.
In Vitro Systems Toxicology Assessment of a Candidate Modified Risk Tobacco Product Shows Reduced Toxicity Compared to That of a Conventional Cigarette.
Gonzalez-Suarez I, Martin F, Marescotti D, Guedj E, Acali S, Johne S, Dulize R, Baumer K, Peric D, Goedertier D, Frentzel S, Ivanov NV, Mathis C, Hoeng J, Peitsch MC. Gonzalez-Suarez I, et al. Among authors: frentzel s. Chem Res Toxicol. 2016 Jan 19;29(1):3-18. doi: 10.1021/acs.chemrestox.5b00321. Epub 2015 Dec 29. Chem Res Toxicol. 2016. PMID: 26651182
A framework for in vitro systems toxicology assessment of e-liquids.
Iskandar AR, Gonzalez-Suarez I, Majeed S, Marescotti D, Sewer A, Xiang Y, Leroy P, Guedj E, Mathis C, Schaller JP, Vanscheeuwijck P, Frentzel S, Martin F, Ivanov NV, Peitsch MC, Hoeng J. Iskandar AR, et al. Among authors: frentzel s. Toxicol Mech Methods. 2016 Jul;26(6):389-413. doi: 10.3109/15376516.2016.1170251. Epub 2016 Apr 26. Toxicol Mech Methods. 2016. PMID: 27117495 Free PMC article.
A systems toxicology approach for comparative assessment: Biological impact of an aerosol from a candidate modified-risk tobacco product and cigarette smoke on human organotypic bronchial epithelial cultures.
Iskandar AR, Mathis C, Schlage WK, Frentzel S, Leroy P, Xiang Y, Sewer A, Majeed S, Ortega-Torres L, Johne S, Guedj E, Trivedi K, Kratzer G, Merg C, Elamin A, Martin F, Ivanov NV, Peitsch MC, Hoeng J. Iskandar AR, et al. Among authors: frentzel s. Toxicol In Vitro. 2017 Mar;39:29-51. doi: 10.1016/j.tiv.2016.11.009. Epub 2016 Nov 16. Toxicol In Vitro. 2017. PMID: 27865774 Free article.
A lung/liver-on-a-chip platform for acute and chronic toxicity studies.
Bovard D, Sandoz A, Luettich K, Frentzel S, Iskandar A, Marescotti D, Trivedi K, Guedj E, Dutertre Q, Peitsch MC, Hoeng J. Bovard D, et al. Among authors: frentzel s. Lab Chip. 2018 Dec 4;18(24):3814-3829. doi: 10.1039/c8lc01029c. Lab Chip. 2018. PMID: 30460365
69 results