Watanabe N - Search Results

1

Correction to: Comparative Study of the Dose-Dependence of OATP1B Inhibition by Rifampicin Using Probe Drugs and Endogenous Substrates in Healthy Volunteers.

Takehara I, Yoshikado T, Ishigame K, Mori D, Furihata KI, Watanabe N, Ando O, Maeda K, Kusuhara H, Sugiyama Y. Takehara I, et al. Among authors: watanabe n. Pharm Res. 2019 Feb 21;36(4):55. doi: 10.1007/s11095-019-2585-8. Pharm Res. 2019. PMID: 30790061

2

Evaluation of the usefulness of breast cancer resistance protein (BCRP) knockout mice and BCRP inhibitor-treated monkeys to estimate the clinical impact of BCRP modulation on the pharmacokinetics of BCRP substrates.

Karibe T, Hagihara-Nakagomi R, Abe K, Imaoka T, Mikkaichi T, Yasuda S, Hirouchi M, Watanabe N, Okudaira N, Izumi T. Karibe T, et al. Among authors: watanabe n. Pharm Res. 2015 May;32(5):1634-47. doi: 10.1007/s11095-014-1563-4. Epub 2014 Nov 8. Pharm Res. 2015. PMID: 25380981

3

Investigation of Glycochenodeoxycholate Sulfate and Chenodeoxycholate Glucuronide as Surrogate Endogenous Probes for Drug Interaction Studies of OATP1B1 and OATP1B3 in Healthy Japanese Volunteers.

Takehara I, Terashima H, Nakayama T, Yoshikado T, Yoshida M, Furihata K, Watanabe N, Maeda K, Ando O, Sugiyama Y, Kusuhara H. Takehara I, et al. Among authors: watanabe n. Pharm Res. 2017 Aug;34(8):1601-1614. doi: 10.1007/s11095-017-2184-5. Epub 2017 May 26. Pharm Res. 2017. PMID: 28550384

4

Comparative Study of the Dose-Dependence of OATP1B Inhibition by Rifampicin Using Probe Drugs and Endogenous Substrates in Healthy Volunteers.

Takehara I, Yoshikado T, Ishigame K, Mori D, Furihata KI, Watanabe N, Ando O, Maeda K, Sugiyama Y, Kusuhara H. Takehara I, et al. Among authors: watanabe n. Pharm Res. 2018 May 10;35(7):138. doi: 10.1007/s11095-018-2416-3. Pharm Res. 2018. PMID: 29748935 Clinical Trial.

5

In vivo multiple metabolic pathways for a novel G protein-coupled receptor 119 agonist DS-8500a in rats: involvement of the 1,2,4-oxadiazole ring-opening reductive reaction in livers under anaerobic conditions.

Makino C, Watanabe A, Deguchi T, Shiozawa H, Schreck I, Rozehnal V, Ishizuka T, Watanabe N, Ando O, Murayama N, Yamazaki H. Makino C, et al. Among authors: watanabe n, watanabe a. Xenobiotica. 2019 Aug;49(8):961-969. doi: 10.1080/00498254.2018.1514545. Epub 2018 Sep 28. Xenobiotica. 2019. PMID: 30124356

6

Effect of Rifampicin on the Plasma Concentrations of Bile Acid-O-Sulfates in Monkeys and Human Liver-Transplanted Chimeric Mice With or Without Bile Flow Diversion.

Takehara I, Watanabe N, Mori D, Ando O, Kusuhara H. Takehara I, et al. Among authors: watanabe n. J Pharm Sci. 2019 Aug;108(8):2756-2764. doi: 10.1016/j.xphs.2019.03.021. Epub 2019 Mar 21. J Pharm Sci. 2019. PMID: 30905707

7

Elucidation of N ¹-methyladenosine as a Potential Surrogate Biomarker for Drug Interaction Studies Involving Renal Organic Cation Transporters.

Miyake T, Mizuno T, Takehara I, Mochizuki T, Kimura M, Matsuki S, Irie S, Watanabe N, Kato Y, Ieiri I, Maeda K, Ando O, Kusuhara H. Miyake T, et al. Among authors: watanabe n. Drug Metab Dispos. 2019 Nov;47(11):1270-1280. doi: 10.1124/dmd.119.087262. Epub 2019 Sep 11. Drug Metab Dispos. 2019. PMID: 31511257

8

Functional analysis of aldehyde oxidase using expressed chimeric enzyme between monkey and rat.

Itoh K, Asakawa T, Hoshino K, Adachi M, Fukiya K, Watanabe N, Tanaka Y. Itoh K, et al. Among authors: watanabe n. Biol Pharm Bull. 2009 Jan;32(1):31-5. doi: 10.1248/bpb.32.31. Biol Pharm Bull. 2009. PMID: 19122276 Free article.

9

Hydrolysis of synthetic substrate, L-pyroglutamyl p-nitroanilide is catalyzed solely by pyroglutamyl aminopeptidase I in rat liver cytosol.

Abe K, Watanabe N, Kosaka T, Yamada M, Tokui T, Ikeda T. Abe K, et al. Among authors: watanabe n. Biol Pharm Bull. 2003 Nov;26(11):1528-33. doi: 10.1248/bpb.26.1528. Biol Pharm Bull. 2003. PMID: 14600395 Free article.

10

Cloning, expression, and characterization of male cynomolgus monkey liver aldehyde oxidase.

Hoshino K, Itoh K, Masubuchi A, Adachi M, Asakawa T, Watanabe N, Kosaka T, Tanaka Y. Hoshino K, et al. Among authors: watanabe n. Biol Pharm Bull. 2007 Jul;30(7):1191-8. doi: 10.1248/bpb.30.1191. Biol Pharm Bull. 2007. PMID: 17603152 Free article.

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