Zaro BW - Search Results

1

Dimethyl Fumarate Disrupts Human Innate Immune Signaling by Targeting the IRAK4-MyD88 Complex.

Zaro BW, Vinogradova EV, Lazar DC, Blewett MM, Suciu RM, Takaya J, Studer S, de la Torre JC, Casanova JL, Cravatt BF, Teijaro JR. Zaro BW, et al. J Immunol. 2019 May 1;202(9):2737-2746. doi: 10.4049/jimmunol.1801627. Epub 2019 Mar 18. J Immunol. 2019. PMID: 30885957 Free PMC article.

2

Chemical proteomic map of dimethyl fumarate-sensitive cysteines in primary human T cells.

Blewett MM, Xie J, Zaro BW, Backus KM, Altman A, Teijaro JR, Cravatt BF. Blewett MM, et al. Among authors: zaro bw. Sci Signal. 2016 Sep 13;9(445):rs10. doi: 10.1126/scisignal.aaf7694. Sci Signal. 2016. PMID: 27625306 Free PMC article.

3

The Proteome-Wide Potential for Reversible Covalency at Cysteine.

Senkane K, Vinogradova EV, Suciu RM, Crowley VM, Zaro BW, Bradshaw JM, Brameld KA, Cravatt BF. Senkane K, et al. Among authors: zaro bw. Angew Chem Int Ed Engl. 2019 Aug 12;58(33):11385-11389. doi: 10.1002/anie.201905829. Epub 2019 Jul 5. Angew Chem Int Ed Engl. 2019. PMID: 31222866 Free PMC article.

4

Metabolically Labile Fumarate Esters Impart Kinetic Selectivity to Irreversible Inhibitors.

Zaro BW, Whitby LR, Lum KM, Cravatt BF. Zaro BW, et al. J Am Chem Soc. 2016 Dec 14;138(49):15841-15844. doi: 10.1021/jacs.6b10589. Epub 2016 Dec 5. J Am Chem Soc. 2016. PMID: 27960302 Free PMC article.

5

Refinement of Covalent EGFR Inhibitor AZD9291 to Eliminate Off-target Activity.

Bouffard E, Zaro BW, Dix MM, Cravatt B, Wong CH. Bouffard E, et al. Among authors: zaro bw. Tetrahedron Lett. 2021 Jun 22;74:153178. doi: 10.1016/j.tetlet.2021.153178. Epub 2021 May 13. Tetrahedron Lett. 2021. PMID: 34764521 Free PMC article.

6

Improved Electrophile Design for Exquisite Covalent Molecule Selectivity.

Montaño JL, Wang BJ, Volk RF, Warrington SE, Garda VG, Hofmann KL, Chen LC, Zaro BW. Montaño JL, et al. Among authors: zaro bw. ACS Chem Biol. 2022 Jun 17;17(6):1440-1449. doi: 10.1021/acschembio.1c00980. Epub 2022 May 19. ACS Chem Biol. 2022. PMID: 35587148

7

An alkyne-aspirin chemical reporter for the detection of aspirin-dependent protein modification in living cells.

Bateman LA, Zaro BW, Miller SM, Pratt MR. Bateman LA, et al. Among authors: zaro bw. J Am Chem Soc. 2013 Oct 2;135(39):14568-73. doi: 10.1021/ja408322b. Epub 2013 Sep 18. J Am Chem Soc. 2013. PMID: 23998633

8

Changes in metabolic chemical reporter structure yield a selective probe of O-GlcNAc modification.

Chuh KN, Zaro BW, Piller F, Piller V, Pratt MR. Chuh KN, et al. Among authors: zaro bw. J Am Chem Soc. 2014 Sep 3;136(35):12283-95. doi: 10.1021/ja504063c. Epub 2014 Aug 25. J Am Chem Soc. 2014. PMID: 25153642 Free PMC article.

9

The New Chemical Reporter 6-Alkynyl-6-deoxy-GlcNAc Reveals O-GlcNAc Modification of the Apoptotic Caspases That Can Block the Cleavage/Activation of Caspase-8.

Chuh KN, Batt AR, Zaro BW, Darabedian N, Marotta NP, Brennan CK, Amirhekmat A, Pratt MR. Chuh KN, et al. Among authors: zaro bw. J Am Chem Soc. 2017 Jun 14;139(23):7872-7885. doi: 10.1021/jacs.7b02213. Epub 2017 May 31. J Am Chem Soc. 2017. PMID: 28528544 Free PMC article.

10

Precise control of protein concentration in living cells.

Lau HD, Yaegashi J, Zaro BW, Pratt MR. Lau HD, et al. Among authors: zaro bw. Angew Chem Int Ed Engl. 2010 Nov 2;49(45):8458-61. doi: 10.1002/anie.201003073. Angew Chem Int Ed Engl. 2010. PMID: 20878685 No abstract available.

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