Newton AC - Search Results

1

Protein Kinase C Quality Control by Phosphatase PHLPP1 Unveils Loss-of-Function Mechanism in Cancer.

Baffi TR, Van AN, Zhao W, Mills GB, Newton AC. Baffi TR, et al. Among authors: newton ac. Mol Cell. 2019 Apr 18;74(2):378-392.e5. doi: 10.1016/j.molcel.2019.02.018. Epub 2019 Mar 20. Mol Cell. 2019. PMID: 30904392 Free PMC article.

2

Protein kinase C: structure, function, and regulation.

Newton AC. Newton AC. J Biol Chem. 1995 Dec 1;270(48):28495-8. doi: 10.1074/jbc.270.48.28495. J Biol Chem. 1995. PMID: 7499357 Free article. Review. No abstract available.

3

Regulation of protein kinase C.

Newton AC. Newton AC. Curr Opin Cell Biol. 1997 Apr;9(2):161-7. doi: 10.1016/s0955-0674(97)80058-0. Curr Opin Cell Biol. 1997. PMID: 9069266 Review.

4

Dual role of pseudosubstrate in the coordinated regulation of protein kinase C by phosphorylation and diacylglycerol.

Dutil EM, Newton AC. Dutil EM, et al. Among authors: newton ac. J Biol Chem. 2000 Apr 7;275(14):10697-701. doi: 10.1074/jbc.275.14.10697. J Biol Chem. 2000. PMID: 10744767 Free article.

5

A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C.

Violin JD, Zhang J, Tsien RY, Newton AC. Violin JD, et al. Among authors: newton ac. J Cell Biol. 2003 Jun 9;161(5):899-909. doi: 10.1083/jcb.200302125. Epub 2003 Jun 2. J Cell Biol. 2003. PMID: 12782683 Free PMC article.

6

Pathway illuminated: visualizing protein kinase C signaling.

Violin JD, Newton AC. Violin JD, et al. Among authors: newton ac. IUBMB Life. 2003 Dec;55(12):653-60. doi: 10.1080/152165401310001642216. IUBMB Life. 2003. PMID: 14769001 Free article. Review.

7

PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth.

Gao T, Furnari F, Newton AC. Gao T, et al. Among authors: newton ac. Mol Cell. 2005 Apr 1;18(1):13-24. doi: 10.1016/j.molcel.2005.03.008. Mol Cell. 2005. PMID: 15808505 Free article.

8

PHLPP and a second isoform, PHLPP2, differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms.

Brognard J, Sierecki E, Gao T, Newton AC. Brognard J, et al. Among authors: newton ac. Mol Cell. 2007 Mar 23;25(6):917-31. doi: 10.1016/j.molcel.2007.02.017. Mol Cell. 2007. PMID: 17386267 Free article.

9

The phosphatase PHLPP controls the cellular levels of protein kinase C.

Gao T, Brognard J, Newton AC. Gao T, et al. Among authors: newton ac. J Biol Chem. 2008 Mar 7;283(10):6300-11. doi: 10.1074/jbc.M707319200. Epub 2007 Dec 27. J Biol Chem. 2008. PMID: 18162466 Free article.

10

PHLiPPing the switch on Akt and protein kinase C signaling.

Brognard J, Newton AC. Brognard J, et al. Among authors: newton ac. Trends Endocrinol Metab. 2008 Aug;19(6):223-30. doi: 10.1016/j.tem.2008.04.001. Epub 2008 May 27. Trends Endocrinol Metab. 2008. PMID: 18511290 Free PMC article. Review.

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