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In Vitro and In Silico Acetylcholinesterase Inhibitory Activity of Thalictricavine and Canadine and Their Predicted Penetration across the Blood-Brain Barrier.
Chlebek J, Korábečný J, Doležal R, Štěpánková Š, Pérez DI, Hošťálková A, Opletal L, Cahlíková L, Macáková K, Kučera T, Hrabinová M, Jun D. Chlebek J, et al. Among authors: perez di. Molecules. 2019 Apr 5;24(7):1340. doi: 10.3390/molecules24071340. Molecules. 2019. PMID: 30959739 Free PMC article.
Application of BACE1 immobilized enzyme reactor for the characterization of multifunctional alkaloids from Corydalis cava (Fumariaceae) as Alzheimer's disease targets.
Chlebek J, De Simone A, Hošťálková A, Opletal L, Pérez C, Pérez DI, Havlíková L, Cahlíková L, Andrisano V. Chlebek J, et al. Among authors: perez di, perez c. Fitoterapia. 2016 Mar;109:241-7. doi: 10.1016/j.fitote.2016.01.008. Epub 2016 Jan 11. Fitoterapia. 2016. PMID: 26779945 Free article.
5-Imino-1,2-4-thiadiazoles and quinazolines derivatives as glycogen synthase kinase 3β (GSK-3β) and phosphodiesterase 7 (PDE7) inhibitors: determination of blood-brain barrier penetration and binding to human serum albumin.
Pérez DI, Pistolozzi M, Palomo V, Redondo M, Fortugno C, Gil C, Felix G, Martinez A, Bertucci C. Pérez DI, et al. Eur J Pharm Sci. 2012 Apr 11;45(5):677-84. doi: 10.1016/j.ejps.2012.01.007. Epub 2012 Jan 28. Eur J Pharm Sci. 2012. PMID: 22306656
Chameleon-like behavior of indolylpiperidines in complex with cholinesterases targets: Potent butyrylcholinesterase inhibitors.
Chierrito TPC, Pedersoli-Mantoani S, Roca C, Sebastian-Pérez V, Martínez-Gonzalez L, Pérez DI, Perez C, Canales A, Cañada FJ, Campillo NE, Carvalho I, Martinez A. Chierrito TPC, et al. Among authors: perez di, perez c. Eur J Med Chem. 2018 Feb 10;145:431-444. doi: 10.1016/j.ejmech.2018.01.007. Epub 2018 Jan 5. Eur J Med Chem. 2018. PMID: 29335209
Modulation of cAMP-specific PDE without emetogenic activity: new sulfide-like PDE7 inhibitors.
García AM, Brea J, Morales-García JA, Perez DI, González A, Alonso-Gil S, Gracia-Rubio I, Ros-Simó C, Conde S, Cadavid MI, Loza MI, Perez-Castillo A, Valverde O, Martinez A, Gil C. García AM, et al. Among authors: perez castillo a, perez di. J Med Chem. 2014 Oct 23;57(20):8590-607. doi: 10.1021/jm501090m. Epub 2014 Oct 8. J Med Chem. 2014. PMID: 25264825
64 results