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Next generation physiologically based kinetic (NG-PBK) models in support of regulatory decision making.
Comput Toxicol. 2019 Feb;9:61-72. doi: 10.1016/j.comtox.2018.11.002.
Comput Toxicol. 2019.
PMID: 31008414
Free PMC article.
Review.
Investigating the state of physiologically based kinetic modelling practices and challenges associated with gaining regulatory acceptance of model applications.
Paini A, Leonard JA, Kliment T, Tan YM, Worth A.
Paini A, et al. Among authors: kliment t.
Regul Toxicol Pharmacol. 2017 Nov;90:104-115. doi: 10.1016/j.yrtph.2017.08.019. Epub 2017 Sep 1.
Regul Toxicol Pharmacol. 2017.
PMID: 28866268
Free PMC article.
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Capturing the applicability of in vitro-in silico membrane transporter data in chemical risk assessment and biomedical research.
Clerbaux LA, Coecke S, Lumen A, Kliment T, Worth AP, Paini A.
Clerbaux LA, et al. Among authors: kliment t.
Sci Total Environ. 2018 Dec 15;645:97-108. doi: 10.1016/j.scitotenv.2018.07.122. Epub 2018 Jul 14.
Sci Total Environ. 2018.
PMID: 30015123
Free PMC article.
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