Chaput J - Search Results

1

Synthesis of a Fluorescent Cytidine TNA Triphosphate Analogue.

Mei H, Chaput J. Mei H, et al. Among authors: chaput j. Methods Mol Biol. 2019;1973:27-37. doi: 10.1007/978-1-4939-9216-4_3. Methods Mol Biol. 2019. PMID: 31016694

2

DNA polymerase-mediated DNA synthesis on a TNA template.

Chaput JC, Ichida JK, Szostak JW. Chaput JC, et al. J Am Chem Soc. 2003 Jan 29;125(4):856-7. doi: 10.1021/ja028589k. J Am Chem Soc. 2003. PMID: 12537469

3

TNA synthesis by DNA polymerases.

Chaput JC, Szostak JW. Chaput JC, et al. J Am Chem Soc. 2003 Aug 6;125(31):9274-5. doi: 10.1021/ja035917n. J Am Chem Soc. 2003. PMID: 12889939

4

Experimental evidence that GNA and TNA were not sequential polymers in the prebiotic evolution of RNA.

Yang YW, Zhang S, McCullum EO, Chaput JC. Yang YW, et al. J Mol Evol. 2007 Sep;65(3):289-95. doi: 10.1007/s00239-007-9017-9. Epub 2007 Sep 9. J Mol Evol. 2007. PMID: 17828568

5

Random mutagenesis by error-prone PCR.

McCullum EO, Williams BA, Zhang J, Chaput JC. McCullum EO, et al. Among authors: chaput jc. Methods Mol Biol. 2010;634:103-9. doi: 10.1007/978-1-60761-652-8_7. Methods Mol Biol. 2010. PMID: 20676978

6

Synthesis and enzymatic incorporation of α-L-threofuranosyl adenine triphosphate (tATP).

Zhang S, Chaput JC. Zhang S, et al. Bioorg Med Chem Lett. 2013 Mar 1;23(5):1447-9. doi: 10.1016/j.bmcl.2012.12.080. Epub 2013 Jan 5. Bioorg Med Chem Lett. 2013. PMID: 23352269

7

DNA polymerase-mediated synthesis of unbiased threose nucleic acid (TNA) polymers requires 7-deazaguanine to suppress G:G mispairing during TNA transcription.

Dunn MR, Larsen AC, Zahurancik WJ, Fahmi NE, Meyers M, Suo Z, Chaput JC. Dunn MR, et al. Among authors: chaput jc. J Am Chem Soc. 2015 Apr 1;137(12):4014-7. doi: 10.1021/ja511481n. Epub 2015 Mar 20. J Am Chem Soc. 2015. PMID: 25785966

8

Improving Polymerase Activity with Unnatural Substrates by Sampling Mutations in Homologous Protein Architectures.

Dunn MR, Otto C, Fenton KE, Chaput JC. Dunn MR, et al. ACS Chem Biol. 2016 May 20;11(5):1210-9. doi: 10.1021/acschembio.5b00949. Epub 2016 Feb 17. ACS Chem Biol. 2016. PMID: 26860781

9

A Scalable Synthesis of α-L-Threose Nucleic Acid Monomers.

Sau SP, Fahmi NE, Liao JY, Bala S, Chaput JC. Sau SP, et al. J Org Chem. 2016 Mar 18;81(6):2302-7. doi: 10.1021/acs.joc.5b02768. Epub 2016 Feb 26. J Org Chem. 2016. PMID: 26895480

10

Evaluating TNA stability under simulated physiological conditions.

Culbertson MC, Temburnikar KW, Sau SP, Liao JY, Bala S, Chaput JC. Culbertson MC, et al. Bioorg Med Chem Lett. 2016 May 15;26(10):2418-2421. doi: 10.1016/j.bmcl.2016.03.118. Epub 2016 Apr 1. Bioorg Med Chem Lett. 2016. PMID: 27080186

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