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A CD40L-targeting protein reduces autoantibodies and improves disease activity in patients with autoimmunity.
Karnell JL, Albulescu M, Drabic S, Wang L, Moate R, Baca M, Oganesyan V, Gunsior M, Thisted T, Yan L, Li J, Xiong X, Eck SC, de Los Reyes M, Yusuf I, Streicher K, Müller-Ladner U, Howe D, Ettinger R, Herbst R, Drappa J. Karnell JL, et al. Sci Transl Med. 2019 Apr 24;11(489):eaar6584. doi: 10.1126/scitranslmed.aar6584. Sci Transl Med. 2019. PMID: 31019027
Adipokines and Autoimmunity in Inflammatory Arthritis.
Neumann E, Hasseli R, Ohl S, Lange U, Frommer KW, Müller-Ladner U. Neumann E, et al. Cells. 2021 Jan 22;10(2):216. doi: 10.3390/cells10020216. Cells. 2021. PMID: 33499006 Free PMC article. Review.
Effects of BI 655064, an antagonistic anti-CD40 antibody, on clinical and biomarker variables in patients with active rheumatoid arthritis: a randomised, double-blind, placebo-controlled, phase IIa study.
Visvanathan S, Daniluk S, Ptaszyński R, Müller-Ladner U, Ramanujam M, Rosenstock B, Eleftheraki AG, Vinisko R, Petříková A, Kellner H, Dokoupilova E, Kwiatkowska B, Alten R, Schwabe C, Baum P, Joseph D, Fine JS, Padula SJ, Steffgen J. Visvanathan S, et al. Ann Rheum Dis. 2019 Jun;78(6):754-760. doi: 10.1136/annrheumdis-2018-214729. Epub 2019 Mar 22. Ann Rheum Dis. 2019. PMID: 30902820 Free PMC article. Clinical Trial.
Synovial fibroblasts spread rheumatoid arthritis to unaffected joints.
Lefèvre S, Knedla A, Tennie C, Kampmann A, Wunrau C, Dinser R, Korb A, Schnäker EM, Tarner IH, Robbins PD, Evans CH, Stürz H, Steinmeyer J, Gay S, Schölmerich J, Pap T, Müller-Ladner U, Neumann E. Lefèvre S, et al. Nat Med. 2009 Dec;15(12):1414-20. doi: 10.1038/nm.2050. Epub 2009 Nov 8. Nat Med. 2009. PMID: 19898488 Free PMC article.
Dr. Wegner, et al, reply.
Wegner F, Müller-Ladner U, Meier FMP. Wegner F, et al. J Rheumatol. 2018 Jun;45(6):875. doi: 10.3899/jrheum.171439. J Rheumatol. 2018. PMID: 29858457 No abstract available.
The Adipokine Network in Rheumatic Joint Diseases.
Carrión M, Frommer KW, Pérez-García S, Müller-Ladner U, Gomariz RP, Neumann E. Carrión M, et al. Int J Mol Sci. 2019 Aug 22;20(17):4091. doi: 10.3390/ijms20174091. Int J Mol Sci. 2019. PMID: 31443349 Free PMC article. Review.
641 results