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Infants born to mothers with IBD present with altered gut microbiome that transfers abnormalities of the adaptive immune system to germ-free mice.
Torres J, Hu J, Seki A, Eisele C, Nair N, Huang R, Tarassishin L, Jharap B, Cote-Daigneault J, Mao Q, Mogno I, Britton GJ, Uzzan M, Chen CL, Kornbluth A, George J, Legnani P, Maser E, Loudon H, Stone J, Dubinsky M, Faith JJ, Clemente JC, Mehandru S, Colombel JF, Peter I. Torres J, et al. Among authors: dubinsky m. Gut. 2020 Jan;69(1):42-51. doi: 10.1136/gutjnl-2018-317855. Epub 2019 Apr 29. Gut. 2020. PMID: 31036757
Microbiotas from Humans with Inflammatory Bowel Disease Alter the Balance of Gut Th17 and RORγt+ Regulatory T Cells and Exacerbate Colitis in Mice.
Britton GJ, Contijoch EJ, Mogno I, Vennaro OH, Llewellyn SR, Ng R, Li Z, Mortha A, Merad M, Das A, Gevers D, McGovern DPB, Singh N, Braun J, Jacobs JP, Clemente JC, Grinspan A, Sands BE, Colombel JF, Dubinsky MC, Faith JJ. Britton GJ, et al. Among authors: dubinsky mc. Immunity. 2019 Jan 15;50(1):212-224.e4. doi: 10.1016/j.immuni.2018.12.015. Immunity. 2019. PMID: 30650377 Free PMC article.
Gut microbiota density influences host physiology and is shaped by host and microbial factors.
Contijoch EJ, Britton GJ, Yang C, Mogno I, Li Z, Ng R, Llewellyn SR, Hira S, Johnson C, Rabinowitz KM, Barkan R, Dotan I, Hirten RP, Fu SC, Luo Y, Yang N, Luong T, Labrias PR, Lira S, Peter I, Grinspan A, Clemente JC, Kosoy R, Kim-Schulze S, Qin X, Castillo A, Hurley A, Atreja A, Rogers J, Fasihuddin F, Saliaj M, Nolan A, Reyes-Mercedes P, Rodriguez C, Aly S, Santa-Cruz K, Peters L, Suárez-Fariñas M, Huang R, Hao K, Zhu J, Zhang B, Losic B, Irizar H, Song WM, Di Narzo A, Wang W, Cohen BL, DiMaio C, Greenwald D, Itzkowitz S, Lucas A, Marion J, Maser E, Ungaro R, Naymagon S, Novak J, Shah B, Ullman T, Rubin P, George J, Legnani P, Telesco SE, Friedman JR, Brodmerkel C, Plevy S, Cho JH, Colombel JF, Schadt EE, Argmann C, Dubinsky M, Kasarskis A, Sands B, Faith JJ. Contijoch EJ, et al. Among authors: dubinsky m. Elife. 2019 Jan 22;8:e40553. doi: 10.7554/eLife.40553. Elife. 2019. PMID: 30666957 Free PMC article.
Emergent colectomy rates decreased while elective ileal pouch rates were stable over time: a nationwide inpatient sample study.
Kayal M, Saha A, Poojary P, Paramsothy S, Hirten R, Cohen L, Gallinger Z, Mehandru S, Cho J, Greenstein A, Nadkarni G, Dubinsky MC, Colombel JF, Cohen B, Ungaro R. Kayal M, et al. Among authors: dubinsky mc. Int J Colorectal Dis. 2019 Oct;34(10):1771-1779. doi: 10.1007/s00384-019-03375-2. Epub 2019 Sep 11. Int J Colorectal Dis. 2019. PMID: 31512019 Free PMC article.
Endoscopic activity in asymptomatic patients with an ileal pouch is associated with an increased risk of pouchitis.
Kayal M, Plietz M, Radcliffe M, Rizvi A, Yzet C, Tixier E, Hirten RP, Cohen B, Sylla P, Khaitov S, Greenstein A, Colombel JF, Dubinsky MC, Ungaro RC. Kayal M, et al. Among authors: dubinsky mc. Aliment Pharmacol Ther. 2019 Dec;50(11-12):1189-1194. doi: 10.1111/apt.15505. Epub 2019 Oct 3. Aliment Pharmacol Ther. 2019. PMID: 31579976 Free PMC article.
423 results