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Dual inhibition of glutaminase and carnitine palmitoyltransferase decreases growth and migration of glutaminase inhibition-resistant triple-negative breast cancer cells.
Reis LMD, Adamoski D, Ornitz Oliveira Souza R, Rodrigues Ascenção CF, Sousa de Oliveira KR, Corrêa-da-Silva F, Malta de Sá Patroni F, Meira Dias M, Consonni SR, Mendes de Moraes-Vieira PM, Silber AM, Dias SMG. Reis LMD, et al. Among authors: silber am. J Biol Chem. 2019 Jun 14;294(24):9342-9357. doi: 10.1074/jbc.RA119.008180. Epub 2019 Apr 30. J Biol Chem. 2019. PMID: 31040181 Free PMC article.
Human mitochondrial pyruvate carrier 2 as an autonomous membrane transporter.
Nagampalli RSK, Quesñay JEN, Adamoski D, Islam Z, Birch J, Sebinelli HG, Girard RMBM, Ascenção CFR, Fala AM, Pauletti BA, Consonni SR, de Oliveira JF, Silva ACT, Franchini KG, Leme AFP, Silber AM, Ciancaglini P, Moraes I, Dias SMG, Ambrosio ALB. Nagampalli RSK, et al. Among authors: silber am. Sci Rep. 2018 Feb 22;8(1):3510. doi: 10.1038/s41598-018-21740-z. Sci Rep. 2018. PMID: 29472561 Free PMC article.
Procyclic trypanosomes recycle glucose catabolites and TCA cycle intermediates to stimulate growth in the presence of physiological amounts of proline.
Villafraz O, Biran M, Pineda E, Plazolles N, Cahoreau E, Ornitz Oliveira Souza R, Thonnus M, Allmann S, Tetaud E, Rivière L, Silber AM, Barrett MP, Zíková A, Boshart M, Portais JC, Bringaud F. Villafraz O, et al. Among authors: silber am. PLoS Pathog. 2021 Mar 1;17(3):e1009204. doi: 10.1371/journal.ppat.1009204. eCollection 2021 Mar. PLoS Pathog. 2021. PMID: 33647053 Free PMC article.
Dichloroacetate and Pyruvate Metabolism: Pyruvate Dehydrogenase Kinases as Targets Worth Investigating for Effective Therapy of Toxoplasmosis.
Ferrarini MG, Nisimura LM, Girard RMBM, Alencar MB, Fragoso MSI, Araújo-Silva CA, Veiga AA, Abud APR, Nardelli SC, Vommaro RC, Silber AM, France-Sagot M, Ávila AR. Ferrarini MG, et al. Among authors: silber am. mSphere. 2021 Jan 6;6(1):e01002-20. doi: 10.1128/mSphere.01002-20. mSphere. 2021. PMID: 33408226 Free PMC article.
107 results