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Designer receptor technology for the treatment of epilepsy.
Lieb A, Weston M, Kullmann DM. Lieb A, et al. Among authors: kullmann dm. EBioMedicine. 2019 May;43:641-649. doi: 10.1016/j.ebiom.2019.04.059. Epub 2019 May 9. EBioMedicine. 2019. PMID: 31078519 Free PMC article. Review.
Gene therapy in epilepsy-is it time for clinical trials?
Kullmann DM, Schorge S, Walker MC, Wykes RC. Kullmann DM, et al. Nat Rev Neurol. 2014 May;10(5):300-4. doi: 10.1038/nrneurol.2014.43. Epub 2014 Mar 18. Nat Rev Neurol. 2014. PMID: 24638133 Review.
Optogenetic approaches to treat epilepsy.
Wykes RC, Kullmann DM, Pavlov I, Magloire V. Wykes RC, et al. Among authors: kullmann dm. J Neurosci Methods. 2016 Feb 15;260:215-20. doi: 10.1016/j.jneumeth.2015.06.004. Epub 2015 Jun 10. J Neurosci Methods. 2016. PMID: 26072246 Review.
Biochemical autoregulatory gene therapy for focal epilepsy.
Lieb A, Qiu Y, Dixon CL, Heller JP, Walker MC, Schorge S, Kullmann DM. Lieb A, et al. Among authors: kullmann dm. Nat Med. 2018 Sep;24(9):1324-1329. doi: 10.1038/s41591-018-0103-x. Epub 2018 Jul 9. Nat Med. 2018. PMID: 29988123 Free PMC article.
Epilepsy Gene Therapy Using an Engineered Potassium Channel.
Snowball A, Chabrol E, Wykes RC, Shekh-Ahmad T, Cornford JH, Lieb A, Hughes MP, Massaro G, Rahim AA, Hashemi KS, Kullmann DM, Walker MC, Schorge S. Snowball A, et al. Among authors: kullmann dm. J Neurosci. 2019 Apr 17;39(16):3159-3169. doi: 10.1523/JNEUROSCI.1143-18.2019. Epub 2019 Feb 12. J Neurosci. 2019. PMID: 30755487 Free PMC article.
Novel therapies for epilepsy in the pipeline.
Mesraoua B, Deleu D, Kullmann DM, Shetty AK, Boon P, Perucca E, Mikati MA, Asadi-Pooya AA. Mesraoua B, et al. Among authors: kullmann dm. Epilepsy Behav. 2019 Aug;97:282-290. doi: 10.1016/j.yebeh.2019.04.042. Epub 2019 Jul 6. Epilepsy Behav. 2019. PMID: 31284159 Review.
AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders.
Salpietro V, Dixon CL, Guo H, Bello OD, Vandrovcova J, Efthymiou S, Maroofian R, Heimer G, Burglen L, Valence S, Torti E, Hacke M, Rankin J, Tariq H, Colin E, Procaccio V, Striano P, Mankad K, Lieb A, Chen S, Pisani L, Bettencourt C, Männikkö R, Manole A, Brusco A, Grosso E, Ferrero GB, Armstrong-Moron J, Gueden S, Bar-Yosef O, Tzadok M, Monaghan KG, Santiago-Sim T, Person RE, Cho MT, Willaert R, Yoo Y, Chae JH, Quan Y, Wu H, Wang T, Bernier RA, Xia K, Blesson A, Jain M, Motazacker MM, Jaeger B, Schneider AL, Boysen K, Muir AM, Myers CT, Gavrilova RH, Gunderson L, Schultz-Rogers L, Klee EW, Dyment D, Osmond M, Parellada M, Llorente C, Gonzalez-Peñas J, Carracedo A, Van Haeringen A, Ruivenkamp C, Nava C, Heron D, Nardello R, Iacomino M, Minetti C, Skabar A, Fabretto A; SYNAPS Study Group; Raspall-Chaure M, Chez M, Tsai A, Fassi E, Shinawi M, Constantino JN, De Zorzi R, Fortuna S, Kok F, Keren B, Bonneau D, Choi M, Benzeev B, Zara F, Mefford HC, Scheffer IE, Clayton-Smith J, Macaya A, Rothman JE, Eichler EE, Kullmann DM, Houlden H. Salpietro V, et al. Among authors: kullmann dm. Nat Commun. 2019 Jul 12;10(1):3094. doi: 10.1038/s41467-019-10910-w. Nat Commun. 2019. PMID: 31300657 Free PMC article.
296 results