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Synthesis and biological evaluation of flavone-8-acrylamide derivatives as potential multi-target-directed anti Alzheimer agents and investigation of binding mechanism with acetylcholinesterase.
Shaik JB, Yeggoni DP, Kandrakonda YR, Penumala M, Zinka RB, Kotapati KV, Darla MM, Ampasala DR, Subramanyam R, Amooru DG. Shaik JB, et al. Among authors: ampasala dr. Bioorg Chem. 2019 Jul;88:102960. doi: 10.1016/j.bioorg.2019.102960. Epub 2019 May 3. Bioorg Chem. 2019. PMID: 31102808
Synthesis, pharmacological assessment, molecular modeling and in silico studies of fused tricyclic coumarin derivatives as a new family of multifunctional anti-Alzheimer agents.
Shaik JB, Palaka BK, Penumala M, Kotapati KV, Devineni SR, Eadlapalli S, Darla MM, Ampasala DR, Vadde R, Amooru GD. Shaik JB, et al. Among authors: ampasala dr. Eur J Med Chem. 2016 Jan 1;107:219-32. doi: 10.1016/j.ejmech.2015.10.046. Epub 2015 Oct 31. Eur J Med Chem. 2016. PMID: 26588065
Synthesis, Biological Evaluation, and Molecular Docking of 8-imino-2-oxo-2H,8H-pyrano[2,3-f]chromene Analogs: New Dual AChE Inhibitors as Potential Drugs for the Treatment of Alzheimer's Disease.
Shaik JB, Palaka BK, Penumala M, Eadlapalli S, Darla Mark M, Ampasala DR, Vadde R, Amooru Gangaiah D. Shaik JB, et al. Among authors: ampasala dr. Chem Biol Drug Des. 2016 Jul;88(1):43-53. doi: 10.1111/cbdd.12732. Epub 2016 Feb 24. Chem Biol Drug Des. 2016. PMID: 26833890
33 results