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The Tumor Metabolic Microenvironment: Lessons from Lactate.
García-Cañaveras JC, Chen L, Rabinowitz JD. García-Cañaveras JC, et al. Among authors: rabinowitz jd. Cancer Res. 2019 Jul 1;79(13):3155-3162. doi: 10.1158/0008-5472.CAN-18-3726. Epub 2019 Jun 6. Cancer Res. 2019. PMID: 31171526 Free PMC article. Review.
Treatment of Pancreatic Cancer Patient-Derived Xenograft Panel with Metabolic Inhibitors Reveals Efficacy of Phenformin.
Rajeshkumar NV, Yabuuchi S, Pai SG, De Oliveira E, Kamphorst JJ, Rabinowitz JD, Tejero H, Al-Shahrour F, Hidalgo M, Maitra A, Dang CV. Rajeshkumar NV, et al. Among authors: rabinowitz jd. Clin Cancer Res. 2017 Sep 15;23(18):5639-5647. doi: 10.1158/1078-0432.CCR-17-1115. Epub 2017 Jun 13. Clin Cancer Res. 2017. PMID: 28611197 Free PMC article.
Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy.
Zhang Y, Kurupati R, Liu L, Zhou XY, Zhang G, Hudaihed A, Filisio F, Giles-Davis W, Xu X, Karakousis GC, Schuchter LM, Xu W, Amaravadi R, Xiao M, Sadek N, Krepler C, Herlyn M, Freeman GJ, Rabinowitz JD, Ertl HCJ. Zhang Y, et al. Among authors: rabinowitz jd. Cancer Cell. 2017 Sep 11;32(3):377-391.e9. doi: 10.1016/j.ccell.2017.08.004. Cancer Cell. 2017. PMID: 28898698 Free PMC article.
Chemical Basis for Deuterium Labeling of Fat and NADPH.
Zhang Z, Chen L, Liu L, Su X, Rabinowitz JD. Zhang Z, et al. Among authors: rabinowitz jd. J Am Chem Soc. 2017 Oct 18;139(41):14368-14371. doi: 10.1021/jacs.7b08012. Epub 2017 Oct 4. J Am Chem Soc. 2017. PMID: 28911221 Free PMC article.
Glucose feeds the TCA cycle via circulating lactate.
Hui S, Ghergurovich JM, Morscher RJ, Jang C, Teng X, Lu W, Esparza LA, Reya T, Le Zhan, Yanxiang Guo J, White E, Rabinowitz JD. Hui S, et al. Among authors: rabinowitz jd. Nature. 2017 Nov 2;551(7678):115-118. doi: 10.1038/nature24057. Epub 2017 Oct 18. Nature. 2017. PMID: 29045397 Free PMC article.
296 results