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Bile salts regulate CYP7A1 expression and elicit a fibrotic response and abnormal lipid production in 3D liver microtissues.
Toxicol In Vitro. 2019 Oct;60:261-271. doi: 10.1016/j.tiv.2019.06.002. Epub 2019 Jun 10.
Toxicol In Vitro. 2019.
PMID: 31195089
Assessment of fibrotic pathways induced by environmental chemicals using 3D-human liver microtissue model.
Yan L, Messner CJ, Zhang X, Suter-Dick L.
Yan L, et al. Among authors: messner cj.
Environ Res. 2021 Mar;194:110679. doi: 10.1016/j.envres.2020.110679. Epub 2020 Dec 30.
Environ Res. 2021.
PMID: 33387535
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Single Cell Gene Expression Analysis in a 3D Microtissue Liver Model Reveals Cell Type-Specific Responses to Pro-Fibrotic TGF-β1 Stimulation.
Messner CJ, Babrak L, Titolo G, Caj M, Miho E, Suter-Dick L.
Messner CJ, et al.
Int J Mol Sci. 2021 Apr 22;22(9):4372. doi: 10.3390/ijms22094372.
Int J Mol Sci. 2021.
PMID: 33922101
Free PMC article.
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Identification of miR-199a-5p, miR-214-3p and miR-99b-5p as Fibrosis-Specific Extracellular Biomarkers and Promoters of HSC Activation.
Messner CJ, Schmidt S, Özkul D, Gaiser C, Terracciano L, Krähenbühl S, Suter-Dick L.
Messner CJ, et al.
Int J Mol Sci. 2021 Sep 10;22(18):9799. doi: 10.3390/ijms22189799.
Int J Mol Sci. 2021.
PMID: 34575957
Free PMC article.
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How to Foster 'New Approach Methodology' Toxicologists.
Doktorova TY, Azzi P, Hofer J, Messner CJ, Gaiser C, Werner S, Singh P, Hardy B, Suter-Dick L, Chesne C.
Doktorova TY, et al. Among authors: messner cj.
Altern Lab Anim. 2022 Jan;50(1):71-75. doi: 10.1177/02611929221078945. Epub 2022 Feb 18.
Altern Lab Anim. 2022.
PMID: 35179997
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Evaluation of dioxin induced transcriptomic responses in a 3D human liver microtissue model.
Yan L, Messner CJ, Tian M, Gou X, Suter-Dick L, Zhang X.
Yan L, et al. Among authors: messner cj.
Environ Res. 2022 Jul;210:112906. doi: 10.1016/j.envres.2022.112906. Epub 2022 Feb 16.
Environ Res. 2022.
PMID: 35181307
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Methotrexate-Induced Liver Injury Is Associated with Oxidative Stress, Impaired Mitochondrial Respiration, and Endoplasmic Reticulum Stress In Vitro.
Schmidt S, Messner CJ, Gaiser C, Hämmerli C, Suter-Dick L.
Schmidt S, et al. Among authors: messner cj.
Int J Mol Sci. 2022 Dec 1;23(23):15116. doi: 10.3390/ijms232315116.
Int J Mol Sci. 2022.
PMID: 36499436
Free PMC article.
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