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Targeting drugs for tuberculosis.
Smith TC 2nd, Aldridge BB. Smith TC 2nd, et al. Among authors: aldridge bb. Science. 2019 Jun 28;364(6447):1234-1235. doi: 10.1126/science.aay0211. Science. 2019. PMID: 31249047 No abstract available.
Accelerating Early Antituberculosis Drug Discovery by Creating Mycobacterial Indicator Strains That Predict Mode of Action.
Boot M, Commandeur S, Subudhi AK, Bahira M, Smith TC 2nd, Abdallah AM, van Gemert M, Lelièvre J, Ballell L, Aldridge BB, Pain A, Speer A, Bitter W. Boot M, et al. Among authors: aldridge bb. Antimicrob Agents Chemother. 2018 Jun 26;62(7):e00083-18. doi: 10.1128/AAC.00083-18. Print 2018 Jul. Antimicrob Agents Chemother. 2018. PMID: 29661879 Free PMC article.
Morphological profiling of tubercle bacilli identifies drug pathways of action.
Smith TC 2nd, Pullen KM, Olson MC, McNellis ME, Richardson I, Hu S, Larkins-Ford J, Wang X, Freundlich JS, Ando DM, Aldridge BB. Smith TC 2nd, et al. Among authors: aldridge bb. Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18744-18753. doi: 10.1073/pnas.2002738117. Epub 2020 Jul 17. Proc Natl Acad Sci U S A. 2020. PMID: 32680963 Free PMC article.
Identification of cell wall synthesis inhibitors active against Mycobacterium tuberculosis by competitive activity-based protein profiling.
Li M, Patel HV, Cognetta AB 3rd, Smith TC 2nd, Mallick I, Cavalier JF, Previti ML, Canaan S, Aldridge BB, Cravatt BF, Seeliger JC. Li M, et al. Among authors: aldridge bb. Cell Chem Biol. 2022 May 19;29(5):883-896.e5. doi: 10.1016/j.chembiol.2021.09.002. Epub 2021 Oct 1. Cell Chem Biol. 2022. PMID: 34599873 Free PMC article.
Tuberculosis treatment failure associated with evolution of antibiotic resilience.
Liu Q, Zhu J, Dulberger CL, Stanley S, Wilson S, Chung ES, Wang X, Culviner P, Liu YJ, Hicks ND, Babunovic GH, Giffen SR, Aldridge BB, Garner EC, Rubin EJ, Chao MC, Fortune SM. Liu Q, et al. Among authors: aldridge bb. Science. 2022 Dec 9;378(6624):1111-1118. doi: 10.1126/science.abq2787. Epub 2022 Dec 8. Science. 2022. PMID: 36480634 Free PMC article.
49 results