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A computer-controlled system to simulate conditions of the large intestine with peristaltic mixing, water absorption and absorption of fermentation products.
Minekus M, Smeets-Peeters M, Bernalier A, Marol-Bonnin S, Havenaar R, Marteau P, Alric M, Fonty G, Huis in't Veld JH. Minekus M, et al. Appl Microbiol Biotechnol. 1999 Dec;53(1):108-14. doi: 10.1007/s002530051622. Appl Microbiol Biotechnol. 1999. PMID: 10645630
The system has been designed to be complementary to the dynamic multi-compartmental system that simulates conditions in the stomach and small intestine described by Minekus et al. [Minekus M, Marteau P, Havenaar R, Huis in't Veld JHJ (1995) ATLA 23:197-209]. …
The system has been designed to be complementary to the dynamic multi-compartmental system that simulates conditions in the stomach and smal …
Evaluation of two dynamic in vitro models simulating fasted and fed state conditions in the upper gastrointestinal tract (TIM-1 and tiny-TIM) for investigating the bioaccessibility of pharmaceutical compounds from oral dosage forms.
Verwei M, Minekus M, Zeijdner E, Schilderink R, Havenaar R. Verwei M, et al. Among authors: minekus m. Int J Pharm. 2016 Feb 10;498(1-2):178-86. doi: 10.1016/j.ijpharm.2015.11.048. Epub 2015 Dec 11. Int J Pharm. 2016. PMID: 26688035
A standardised static in vitro digestion method suitable for food - an international consensus.
Minekus M, Alminger M, Alvito P, Ballance S, Bohn T, Bourlieu C, Carrière F, Boutrou R, Corredig M, Dupont D, Dufour C, Egger L, Golding M, Karakaya S, Kirkhus B, Le Feunteun S, Lesmes U, Macierzanka A, Mackie A, Marze S, McClements DJ, Ménard O, Recio I, Santos CN, Singh RP, Vegarud GE, Wickham MS, Weitschies W, Brodkorb A. Minekus M, et al. Food Funct. 2014 Jun;5(6):1113-24. doi: 10.1039/c3fo60702j. Epub 2014 May 7. Food Funct. 2014. PMID: 24803111
28 results