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Particle-Based Simulation Reveals Macromolecular Crowding Effects on the Michaelis-Menten Mechanism.
Biophys J. 2019 Jul 23;117(2):355-368. doi: 10.1016/j.bpj.2019.06.017. Epub 2019 Jun 25.
Biophys J. 2019.
PMID: 31311624
Free PMC article.
Single-molecule kinetic analysis of HP1-chromatin binding reveals a dynamic network of histone modification and DNA interactions.
Bryan LC, Weilandt DR, Bachmann AL, Kilic S, Lechner CC, Odermatt PD, Fantner GE, Georgeon S, Hantschel O, Hatzimanikatis V, Fierz B.
Bryan LC, et al. Among authors: weilandt dr.
Nucleic Acids Res. 2017 Oct 13;45(18):10504-10517. doi: 10.1093/nar/gkx697.
Nucleic Acids Res. 2017.
PMID: 28985346
Free PMC article.
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Symbolic kinetic models in python (SKiMpy): intuitive modeling of large-scale biological kinetic models.
Weilandt DR, Salvy P, Masid M, Fengos G, Denhardt-Erikson R, Hosseini Z, Hatzimanikatis V.
Weilandt DR, et al.
Bioinformatics. 2023 Jan 1;39(1):btac787. doi: 10.1093/bioinformatics/btac787.
Bioinformatics. 2023.
PMID: 36495209
Free PMC article.
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Optimal enzyme utilization suggests that concentrations and thermodynamics determine binding mechanisms and enzyme saturations.
Sahin A, Weilandt DR, Hatzimanikatis V.
Sahin A, et al. Among authors: weilandt dr.
Nat Commun. 2023 May 5;14(1):2618. doi: 10.1038/s41467-023-38159-4.
Nat Commun. 2023.
PMID: 37147292
Free PMC article.
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Reconstructing Kinetic Models for Dynamical Studies of Metabolism using Generative Adversarial Networks.
Choudhury S, Moret M, Salvy P, Weilandt D, Hatzimanikatis V, Miskovic L.
Choudhury S, et al.
Nat Mach Intell. 2022;4(8):710-719. doi: 10.1038/s42256-022-00519-y. Epub 2022 Aug 30.
Nat Mach Intell. 2022.
PMID: 37790987
Free PMC article.
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Slow TCA flux and ATP production in primary solid tumours but not metastases.
Bartman CR, Weilandt DR, Shen Y, Lee WD, Han Y, TeSlaa T, Jankowski CSR, Samarah L, Park NR, da Silva-Diz V, Aleksandrova M, Gultekin Y, Marishta A, Wang L, Yang L, Roichman A, Bhatt V, Lan T, Hu Z, Xing X, Lu W, Davidson S, Wühr M, Vander Heiden MG, Herranz D, Guo JY, Kang Y, Rabinowitz JD.
Bartman CR, et al. Among authors: weilandt dr.
Nature. 2023 Feb;614(7947):349-357. doi: 10.1038/s41586-022-05661-6. Epub 2023 Feb 1.
Nature. 2023.
PMID: 36725930
Free PMC article.
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