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Crystallization of human complement component C3b in the presence of a staphylococcal complement-inhibitor protein (SCIN).
Garcia BL, Tzekou A, Ramyar KX, McWhorter WJ, Ricklin D, Lambris JD, Geisbrecht BV. Garcia BL, et al. Among authors: ramyar kx. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 May 1;65(Pt 5):482-5. doi: 10.1107/S174430910901207X. Epub 2009 Apr 24. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009. PMID: 19407382 Free PMC article.
The extracellular adherence protein from Staphylococcus aureus inhibits the classical and lectin pathways of complement by blocking formation of the C3 proconvertase.
Woehl JL, Stapels DAC, Garcia BL, Ramyar KX, Keightley A, Ruyken M, Syriga M, Sfyroera G, Weber AB, Zolkiewski M, Ricklin D, Lambris JD, Rooijakkers SHM, Geisbrecht BV. Woehl JL, et al. Among authors: ramyar kx. J Immunol. 2014 Dec 15;193(12):6161-6171. doi: 10.4049/jimmunol.1401600. Epub 2014 Nov 7. J Immunol. 2014. PMID: 25381436 Free PMC article.
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