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Development and validation of a bioanalytical method for the quantification of the CDK4/6 inhibitors abemaciclib, palbociclib, and ribociclib in human and mouse matrices using liquid chromatography-tandem mass spectrometry.
Martínez-Chávez A, Rosing H, Hillebrand M, Tibben M, Schinkel AH, Beijnen JH. Martínez-Chávez A, et al. Anal Bioanal Chem. 2019 Aug;411(20):5331-5345. doi: 10.1007/s00216-019-01932-w. Epub 2019 Jun 17. Anal Bioanal Chem. 2019. PMID: 31209549 Free PMC article.
Bioanalytical method for the simultaneous quantification of irinotecan and its active metabolite SN-38 in mouse plasma and tissue homogenates using HPLC-fluorescence.
Martínez-Chávez A, Rosing H, Gan C, Wang Y, Schinkel AH, Beijnen JH. Martínez-Chávez A, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2020 Jul 15;1149:122177. doi: 10.1016/j.jchromb.2020.122177. Epub 2020 May 19. J Chromatogr B Analyt Technol Biomed Life Sci. 2020. PMID: 32464539 Free article.
Drug Transporters ABCB1 (P-gp) and OATP, but not Drug-Metabolizing Enzyme CYP3A4, Affect the Pharmacokinetics of the Psychoactive Alkaloid Ibogaine and its Metabolites.
F Martins ML, Heydari P, Li W, Martínez-Chávez A, Venekamp N, Lebre MC, Lucas L, Beijnen JH, Schinkel AH. F Martins ML, et al. Among authors: martinez chavez a. Front Pharmacol. 2022 Mar 4;13:855000. doi: 10.3389/fphar.2022.855000. eCollection 2022. Front Pharmacol. 2022. PMID: 35308219 Free PMC article.
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