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High baseline Tie1 level predicts poor survival in metastatic breast cancer.
Tiainen L, Korhonen EA, Leppänen VM, Luukkaala T, Hämäläinen M, Tanner M, Lahdenperä O, Vihinen P, Jukkola A, Karihtala P, Aho S, Moilanen E, Alitalo K, Kellokumpu-Lehtinen PL. Tiainen L, et al. Among authors: alitalo k. BMC Cancer. 2019 Jul 24;19(1):732. doi: 10.1186/s12885-019-5959-8. BMC Cancer. 2019. PMID: 31340773 Free PMC article. Clinical Trial.
Structural determinants of growth factor binding and specificity by VEGF receptor 2.
Leppänen VM, Prota AE, Jeltsch M, Anisimov A, Kalkkinen N, Strandin T, Lankinen H, Goldman A, Ballmer-Hofer K, Alitalo K. Leppänen VM, et al. Among authors: alitalo k. Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2425-30. doi: 10.1073/pnas.0914318107. Proc Natl Acad Sci U S A. 2010. PMID: 20145116 Free PMC article.
Effective suppression of vascular network formation by combination of antibodies blocking VEGFR ligand binding and receptor dimerization.
Tvorogov D, Anisimov A, Zheng W, Leppänen VM, Tammela T, Laurinavicius S, Holnthoner W, Heloterä H, Holopainen T, Jeltsch M, Kalkkinen N, Lankinen H, Ojala PM, Alitalo K. Tvorogov D, et al. Among authors: alitalo k. Cancer Cell. 2010 Dec 14;18(6):630-40. doi: 10.1016/j.ccr.2010.11.001. Epub 2010 Dec 2. Cancer Cell. 2010. PMID: 21130043 Free article.
Effects of angiopoietin-2-blocking antibody on endothelial cell-cell junctions and lung metastasis.
Holopainen T, Saharinen P, D'Amico G, Lampinen A, Eklund L, Sormunen R, Anisimov A, Zarkada G, Lohela M, Heloterä H, Tammela T, Benjamin LE, Ylä-Herttuala S, Leow CC, Koh GY, Alitalo K. Holopainen T, et al. Among authors: alitalo k. J Natl Cancer Inst. 2012 Mar 21;104(6):461-75. doi: 10.1093/jnci/djs009. Epub 2012 Feb 17. J Natl Cancer Inst. 2012. PMID: 22343031 Free PMC article.
721 results