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Comparing the prognostic value of risk stratifying models for patients with lower-risk myelodysplastic syndromes: Is one model better?
Zeidan AM, Sekeres MA, Wang XF, Al Ali N, Garcia-Manero G, Steensma DP, Roboz G, Barnard J, Padron E, DeZern A, Maciejewski JP, List AF, Komrokji RS; MDS Clinical Research Consortium (Funded by Edward P. Evans Foundation). Zeidan AM, et al. Among authors: dezern a. Am J Hematol. 2015 Nov;90(11):1036-40. doi: 10.1002/ajh.24173. Am J Hematol. 2015. PMID: 26284571 Free article.
Prognosis of patients with intermediate risk IPSS-R myelodysplastic syndrome indicates variable outcomes and need for models beyond IPSS-R.
Benton CB, Khan M, Sallman D, Nazha A, Nogueras González GM, Piao J, Ning J, Aung F, Al Ali N, Jabbour E, Kadia TM, Borthakur G, Ravandi F, Pierce S, Steensma D, DeZern A, Roboz G, Sekeres M, Andreeff M, Kantarjian H, Komrokji RS, Garcia-Manero G. Benton CB, et al. Among authors: dezern a. Am J Hematol. 2018 Oct;93(10):1245-1253. doi: 10.1002/ajh.25234. Epub 2018 Sep 26. Am J Hematol. 2018. PMID: 30051599 Free PMC article.
Hedgehog/GLI1 activation leads to leukemic transformation of myelodysplastic syndrome in vivo and GLI1 inhibition results in antitumor activity.
Lau BW, Huh K, Madero-Marroquin R, De Marchi F, Lim Y, Wang Q, Lobo F, Marchionni L, Smith DB, DeZern A, Levis MJ, Aplan PD, Matsui W, Gondek LP. Lau BW, et al. Among authors: dezern a. Oncogene. 2019 Jan;38(5):687-698. doi: 10.1038/s41388-018-0431-9. Epub 2018 Aug 31. Oncogene. 2019. PMID: 30171262 Free PMC article.
Treatments targeting MDS genetics: a fool's errand?
DeZern AE. DeZern AE. Hematology Am Soc Hematol Educ Program. 2018 Nov 30;2018(1):277-285. doi: 10.1182/asheducation-2018.1.277. Hematology Am Soc Hematol Educ Program. 2018. PMID: 30504322 Free PMC article. Review.
190 results