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Deletion of Apoptosis Inhibitor F1L in Vaccinia Virus Increases Safety and Oncolysis for Cancer Therapy.
Pelin A, Foloppe J, Petryk J, Singaravelu R, Hussein M, Gossart F, Jennings VA, Stubbert LJ, Foster M, Storbeck C, Postigo A, Scut E, Laight B, Way M, Erbs P, Le Boeuf F, Bell JC. Pelin A, et al. Among authors: stubbert lj. Mol Ther Oncolytics. 2019 Jul 3;14:246-252. doi: 10.1016/j.omto.2019.06.004. eCollection 2019 Sep 27. Mol Ther Oncolytics. 2019. PMID: 31428674 Free PMC article.
Complement inhibition enables tumor delivery of LCMV glycoprotein pseudotyped viruses in the presence of antiviral antibodies.
Evgin L, Ilkow CS, Bourgeois-Daigneault MC, de Souza CT, Stubbert L, Huh MS, Jennings VA, Marguerie M, Acuna SA, Keller BA, Lefebvre C, Falls T, Le Boeuf F, Auer RA, Lambris JD, McCart JA, Stojdl DF, Bell JC. Evgin L, et al. Mol Ther Oncolytics. 2016 Nov 16;3:16027. doi: 10.1038/mto.2016.27. eCollection 2016. Mol Ther Oncolytics. 2016. PMID: 27909702 Free PMC article.
Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity.
Ilkow CS, Marguerie M, Batenchuk C, Mayer J, Ben Neriah D, Cousineau S, Falls T, Jennings VA, Boileau M, Bellamy D, Bastin D, de Souza CT, Alkayyal A, Zhang J, Le Boeuf F, Arulanandam R, Stubbert L, Sampath P, Thorne SH, Paramanthan P, Chatterjee A, Strieter RM, Burdick M, Addison CL, Stojdl DF, Atkins HL, Auer RC, Diallo JS, Lichty BD, Bell JC. Ilkow CS, et al. Nat Med. 2015 May;21(5):530-6. doi: 10.1038/nm.3848. Epub 2015 Apr 20. Nat Med. 2015. PMID: 25894825
Re-engineering vesicular stomatitis virus to abrogate neurotoxicity, circumvent humoral immunity, and enhance oncolytic potency.
Muik A, Stubbert LJ, Jahedi RZ, Geiβ Y, Kimpel J, Dold C, Tober R, Volk A, Klein S, Dietrich U, Yadollahi B, Falls T, Miletic H, Stojdl D, Bell JC, von Laer D. Muik A, et al. Among authors: stubbert lj. Cancer Res. 2014 Jul 1;74(13):3567-78. doi: 10.1158/0008-5472.CAN-13-3306. Epub 2014 May 8. Cancer Res. 2014. PMID: 24812275
Regulation of ultraviolet light-induced gene expression by gene size.
McKay BC, Stubbert LJ, Fowler CC, Smith JM, Cardamore RA, Spronck JC. McKay BC, et al. Among authors: stubbert lj. Proc Natl Acad Sci U S A. 2004 Apr 27;101(17):6582-6. doi: 10.1073/pnas.0308181101. Epub 2004 Apr 15. Proc Natl Acad Sci U S A. 2004. PMID: 15087501 Free PMC article.
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