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Tiered approach to evaluate the CYP3A victim and perpetrator drug-drug interaction potential for vonoprazan using PBPK modeling and clinical data to inform labeling.
Mulford DJ, Ramsden D, Zhang L, Michon I, Leifke E, Smith N, Jones HM, Scarpignato C. Mulford DJ, et al. Among authors: zhang l. CPT Pharmacometrics Syst Pharmacol. 2023 Apr;12(4):532-544. doi: 10.1002/psp4.12939. Epub 2023 Mar 10. CPT Pharmacometrics Syst Pharmacol. 2023. PMID: 36896795 Free PMC article.
Acrylamide drives amidase-mediated gut dysbiosis to aggravate colitis.
Li D, Luo Y, Fan H, Dong L, Zhang X, Feng Y, Tian M, Zhang S, Chen W, Zhang L, Gao J, Ma X, Wang X, Ma C, Zheng R, Hu X, Wang J, Chen F. Li D, et al. Among authors: zhang l. Sci Bull (Beijing). 2024 Jun 8:S2095-9273(24)00400-6. doi: 10.1016/j.scib.2024.06.004. Online ahead of print. Sci Bull (Beijing). 2024. PMID: 38909004 No abstract available.
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