Wouters J - Search Results

1

A new potential anti-cancer beta-carboline derivative decreases the expression levels of key proteins involved in glioma aggressiveness: A proteomic investigation.

Carvalho A, Viaene J, Vandenbussche G, De Braekeleer K, Masereel B, Wouters J, Souard F, Vander Heyden Y, Van Antwerpen P, Delporte C, Mathieu V. Carvalho A, et al. Among authors: wouters j. Drug Dev Res. 2020 Feb;81(1):32-42. doi: 10.1002/ddr.21600. Epub 2019 Sep 9. Drug Dev Res. 2020. PMID: 31498913

2

Design, synthesis, and anticonvulsant activity of 1-(pyrid-3-ylsulfonamido)-2-nitroethylenes.

Masereel B, Wouters J, Pochet L, Lambert D. Masereel B, et al. Among authors: wouters j. J Med Chem. 1998 Aug 13;41(17):3239-44. doi: 10.1021/jm981022n. J Med Chem. 1998. PMID: 9703469

3

Antagonism of the TXA2 receptor by seratrodast: a structural approach.

Wouters J, Durant F, Masereel B. Wouters J, et al. Bioorg Med Chem Lett. 1999 Oct 4;9(19):2867-70. doi: 10.1016/s0960-894x(99)00490-4. Bioorg Med Chem Lett. 1999. PMID: 10522708

4

Coumarinic derivatives as mechanism-based inhibitors of alpha-chymotrypsin and human leukocyte elastase.

Pochet L, Doucet C, Dive G, Wouters J, Masereel B, Reboud-Ravaux M, Pirotte B. Pochet L, et al. Among authors: wouters j. Bioorg Med Chem. 2000 Jun;8(6):1489-501. doi: 10.1016/s0968-0896(00)00071-7. Bioorg Med Chem. 2000. PMID: 10896125 Free article.

5

Isosterism among analogues of torasemide: conformational, electronic and lipophilic properties.

Wouters J, Michaux C, Durant F, Dogné JM, Delarge J, Masereel B. Wouters J, et al. Eur J Med Chem. 2000 Oct;35(10):923-9. doi: 10.1016/s0223-5234(00)01174-0. Eur J Med Chem. 2000. PMID: 11121618

6

Design, synthesis and biological evaluation of a sulfonylcyanoguanidine as thromboxane A2 receptor antagonist and thromboxane synthase inhibitor.

Dogné JM, Wouters J, Rolin S, Michaux C, Pochet L, Durant F, Delarge J, Masereel B. Dogné JM, et al. Among authors: wouters j. J Pharm Pharmacol. 2001 May;53(5):669-80. doi: 10.1211/0022357011775992. J Pharm Pharmacol. 2001. PMID: 11370706

7

Structural approach of the mechanism of inhibition of alpha-chymotrypsin by coumarins.

Wouters J, Huygens M, Pochet L, Pirotte B, Durant F, Masereel B. Wouters J, et al. Bioorg Med Chem Lett. 2002 Apr 8;12(7):1109-12. doi: 10.1016/s0960-894x(02)00073-2. Bioorg Med Chem Lett. 2002. PMID: 11909728

8

A pharmacophore model for sulphonyl-urea (-cyanoguanidine) compounds with dual action, thromboxane receptor antagonists and thromboxane synthase inhibitors.

Michaux C, Dogné JM, Rolin S, Masereel B, Wouters J, Durant F. Michaux C, et al. Among authors: wouters j. Eur J Med Chem. 2003 Jul-Aug;38(7-8):703-10. doi: 10.1016/s0223-5234(03)00076-x. Eur J Med Chem. 2003. PMID: 12932901

9

3,6-disubstituted coumarins as mechanism-based inhibitors of thrombin and factor Xa.

Frédérick R, Robert S, Charlier C, de Ruyck J, Wouters J, Pirotte B, Masereel B, Pochet L. Frédérick R, et al. Among authors: wouters j. J Med Chem. 2005 Dec 1;48(24):7592-603. doi: 10.1021/jm050448g. J Med Chem. 2005. PMID: 16302799

10

Investigation of mechanism-based thrombin inhibitors: Implications of a highly conserved water molecule for the binding of coumarins within the S pocket.

Frédérick R, Charlier C, Robert S, Wouters J, Masereel B, Pochet L. Frédérick R, et al. Among authors: wouters j. Bioorg Med Chem Lett. 2006 Apr 1;16(7):2017-21. doi: 10.1016/j.bmcl.2005.12.070. Epub 2006 Jan 18. Bioorg Med Chem Lett. 2006. PMID: 16413781

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