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Page 1
Viral MLKL Homologs Subvert Necroptotic Cell Death by Sequestering Cellular RIPK3.
Petrie EJ, Sandow JJ, Lehmann WIL, Liang LY, Coursier D, Young SN, Kersten WJA, Fitzgibbon C, Samson AL, Jacobsen AV, Lowes KN, Au AE, Jousset Sabroux H, Lalaoui N, Webb AI, Lessene G, Manning G, Lucet IS, Murphy JM. Petrie EJ, et al. Among authors: au ae. Cell Rep. 2019 Sep 24;28(13):3309-3319.e5. doi: 10.1016/j.celrep.2019.08.055. Cell Rep. 2019. PMID: 31553902 Free article.
Nucleocytoplasmic coagulation: an injury-induced aggregation event that disulfide crosslinks proteins and facilitates their removal by plasmin.
Samson AL, Knaupp AS, Sashindranath M, Borg RJ, Au AE, Cops EJ, Saunders HM, Cody SH, McLean CA, Nowell CJ, Hughes VA, Bottomley SP, Medcalf RL. Samson AL, et al. Among authors: au ae. Cell Rep. 2012 Oct 25;2(4):889-901. doi: 10.1016/j.celrep.2012.08.026. Epub 2012 Oct 4. Cell Rep. 2012. PMID: 23041318 Free article.
Mechanism and inhibition of the papain-like protease, PLpro, of SARS-CoV-2.
Klemm T, Ebert G, Calleja DJ, Allison CC, Richardson LW, Bernardini JP, Lu BG, Kuchel NW, Grohmann C, Shibata Y, Gan ZY, Cooney JP, Doerflinger M, Au AE, Blackmore TR, van der Heden van Noort GJ, Geurink PP, Ovaa H, Newman J, Riboldi-Tunnicliffe A, Czabotar PE, Mitchell JP, Feltham R, Lechtenberg BC, Lowes KN, Dewson G, Pellegrini M, Lessene G, Komander D. Klemm T, et al. Among authors: au ae. EMBO J. 2020 Sep 15;39(18):e106275. doi: 10.15252/embj.2020106275. Epub 2020 Aug 26. EMBO J. 2020. PMID: 32845033 Free PMC article.
Insights Into Drug Repurposing, as Well as Specificity and Compound Properties of Piperidine-Based SARS-CoV-2 PLpro Inhibitors.
Calleja DJ, Kuchel N, Lu BGC, Birkinshaw RW, Klemm T, Doerflinger M, Cooney JP, Mackiewicz L, Au AE, Yap YQ, Blackmore TR, Katneni K, Crighton E, Newman J, Jarman KE, Call MJ, Lechtenberg BC, Czabotar PE, Pellegrini M, Charman SA, Lowes KN, Mitchell JP, Nachbur U, Lessene G, Komander D. Calleja DJ, et al. Among authors: au ae. Front Chem. 2022 Apr 12;10:861209. doi: 10.3389/fchem.2022.861209. eCollection 2022. Front Chem. 2022. PMID: 35494659 Free PMC article.
Design and characterization of a heterobifunctional degrader of KEAP1.
Chen H, Nguyen NH, Magtoto CM, Cobbold SA, Bidgood GM, Meza Guzman LG, Richardson LW, Corbin J, Au AE, Lechtenberg BC, Feltham R, Sutherland KD, Grohmann C, Nicholson SE, Sleebs BE. Chen H, et al. Among authors: au ae. Redox Biol. 2023 Feb;59:102552. doi: 10.1016/j.redox.2022.102552. Epub 2022 Nov 26. Redox Biol. 2023. PMID: 36473314 Free PMC article.
16 results