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The Novel ATR Inhibitor BAY 1895344 Is Efficacious as Monotherapy and Combined with DNA Damage-Inducing or Repair-Compromising Therapies in Preclinical Cancer Models.
Wengner AM, Siemeister G, Lücking U, Lefranc J, Wortmann L, Lienau P, Bader B, Bömer U, Moosmayer D, Eberspächer U, Golfier S, Schatz CA, Baumgart SJ, Haendler B, Lejeune P, Schlicker A, von Nussbaum F, Brands M, Ziegelbauer K, Mumberg D. Wengner AM, et al. Among authors: baumgart sj. Mol Cancer Ther. 2020 Jan;19(1):26-38. doi: 10.1158/1535-7163.MCT-19-0019. Epub 2019 Oct 3. Mol Cancer Ther. 2020. PMID: 31582533
The potent AMPK inhibitor BAY-3827 shows strong efficacy in androgen-dependent prostate cancer models.
Lemos C, Schulze VK, Baumgart SJ, Nevedomskaya E, Heinrich T, Lefranc J, Bader B, Christ CD, Briem H, Kuhnke LP, Holton SJ, Bömer U, Lienau P, von Nussbaum F, Nising CF, Bauser M, Hägebarth A, Mumberg D, Haendler B. Lemos C, et al. Among authors: baumgart sj. Cell Oncol (Dordr). 2021 Jun;44(3):581-594. doi: 10.1007/s13402-020-00584-8. Epub 2021 Jan 25. Cell Oncol (Dordr). 2021. PMID: 33492659
Darolutamide Potentiates the Antitumor Efficacy of a PSMA-targeted Thorium-227 Conjugate by a Dual Mode of Action in Prostate Cancer Models.
Hammer S, Schlicker A, Zitzmann-Kolbe S, Baumgart S, Hagemann UB, Scholz A, Haendler B, Lejeune P, Karlsson J, Ellingsen C, Hennekes H, Nielsen CH, Juul MU, Mumberg D, Schatz CA. Hammer S, et al. Clin Cancer Res. 2021 Aug 1;27(15):4367-4378. doi: 10.1158/1078-0432.CCR-21-0342. Epub 2021 May 25. Clin Cancer Res. 2021. PMID: 34035067 Free PMC article.
Dysregulated Transcriptional Control in Prostate Cancer.
Baumgart SJ, Nevedomskaya E, Haendler B. Baumgart SJ, et al. Int J Mol Sci. 2019 Jun 13;20(12):2883. doi: 10.3390/ijms20122883. Int J Mol Sci. 2019. PMID: 31200487 Free PMC article. Review.
CHD1 loss negatively influences metastasis-free survival in R0-resected prostate cancer patients and promotes spontaneous metastasis in vivo.
Oh-Hohenhorst SJ, Tilki D, Ahlers AK, Suling A, Hahn O, Tennstedt P, Matuszcak C, Maar H, Labitzky V, Hanika S, Starzonek S, Baumgart S, Johnsen SA, Kluth M, Sirma H, Simon R, Sauter G, Huland H, Schumacher U, Lange T. Oh-Hohenhorst SJ, et al. Among authors: baumgart s. Cancer Gene Ther. 2022 Jan;29(1):49-61. doi: 10.1038/s41417-020-00288-z. Epub 2021 Jan 7. Cancer Gene Ther. 2022. PMID: 33414516 Free PMC article.
20 results