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NPM-ALK signals through glycogen synthase kinase 3β to promote oncogenesis.
McDonnell SR, Hwang SR, Basrur V, Conlon KP, Fermin D, Wey E, Murga-Zamalloa C, Zeng Z, Zu Y, Elenitoba-Johnson KS, Lim MS. McDonnell SR, et al. Oncogene. 2012 Aug 9;31(32):3733-40. doi: 10.1038/onc.2011.542. Epub 2011 Dec 19. Oncogene. 2012. PMID: 22179823 Free PMC article.
Integrated phosphoproteomic and metabolomic profiling reveals NPM-ALK-mediated phosphorylation of PKM2 and metabolic reprogramming in anaplastic large cell lymphoma.
McDonnell SR, Hwang SR, Rolland D, Murga-Zamalloa C, Basrur V, Conlon KP, Fermin D, Wolfe T, Raskind A, Ruan C, Jiang JK, Thomas CJ, Hogaboam CM, Burant CF, Elenitoba-Johnson KS, Lim MS. McDonnell SR, et al. Blood. 2013 Aug 8;122(6):958-68. doi: 10.1182/blood-2013-01-482026. Epub 2013 Jun 27. Blood. 2013. PMID: 23814019 Free PMC article.
ALK-driven tumors and targeted therapy: focus on crizotinib.
Murga-Zamalloa C, Lim MS. Murga-Zamalloa C, et al. Pharmgenomics Pers Med. 2014 Mar 20;7:87-94. doi: 10.2147/PGPM.S37504. eCollection 2014. Pharmgenomics Pers Med. 2014. PMID: 24715763 Free PMC article. Review.
Pyrimidine tract-binding protein 1 mediates pyruvate kinase M2-dependent phosphorylation of signal transducer and activator of transcription 3 and oncogenesis in anaplastic large cell lymphoma.
Hwang SR, Murga-Zamalloa C, Brown N, Basappa J, McDonnell SR, Mendoza-Reinoso V, Basrur V, Wilcox R, Elenitoba-Johnson K, Lim MS. Hwang SR, et al. Lab Invest. 2017 Aug;97(8):962-970. doi: 10.1038/labinvest.2017.39. Epub 2017 Apr 17. Lab Invest. 2017. PMID: 28414323 Free article.
Polo-like-kinase 1 (PLK-1) and c-myc inhibition with the dual kinase-bromodomain inhibitor volasertib in aggressive lymphomas.
Murga-Zamalloa C, Polk A, Hanel W, Chowdhury P, Brown N, Hristov AC, Bailey NG, Wang T, Phillips T, Devata S, Poonnen P, Gomez-Gelvez J, Inamdar KV, Wilcox RA. Murga-Zamalloa C, et al. Oncotarget. 2017 Dec 6;8(70):114474-114480. doi: 10.18632/oncotarget.22967. eCollection 2017 Dec 29. Oncotarget. 2017. PMID: 29383095 Free PMC article.
52 results