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Page 1
MCT2 mediates concentration-dependent inhibition of glutamine metabolism by MOG.
Fets L, Driscoll PC, Grimm F, Jain A, Nunes PM, Gounis M, Doglioni G, Papageorgiou G, Ragan TJ, Campos S, Silva Dos Santos M, MacRae JI, O'Reilly N, Wright AJ, Benes CH, Courtney KD, House D, Anastasiou D. Fets L, et al. Among authors: doglioni g. Nat Chem Biol. 2018 Nov;14(11):1032-1042. doi: 10.1038/s41589-018-0136-y. Epub 2018 Oct 8. Nat Chem Biol. 2018. PMID: 30297875 Free PMC article.
PHGDH heterogeneity potentiates cancer cell dissemination and metastasis.
Rossi M, Altea-Manzano P, Demicco M, Doglioni G, Bornes L, Fukano M, Vandekeere A, Cuadros AM, Fernández-García J, Riera-Domingo C, Jauset C, Planque M, Alkan HF, Nittner D, Zuo D, Broadfield LA, Parik S, Pane AA, Rizzollo F, Rinaldi G, Zhang T, Teoh ST, Aurora AB, Karras P, Vermeire I, Broekaert D, Elsen JV, Knott MML, Orth MF, Demeyer S, Eelen G, Dobrolecki LE, Bassez A, Brussel TV, Sotlar K, Lewis MT, Bartsch H, Wuhrer M, Veelen PV, Carmeliet P, Cools J, Morrison SJ, Marine JC, Lambrechts D, Mazzone M, Hannon GJ, Lunt SY, Grünewald TGP, Park M, Rheenen JV, Fendt SM. Rossi M, et al. Among authors: doglioni g. Nature. 2022 May;605(7911):747-753. doi: 10.1038/s41586-022-04758-2. Epub 2022 May 18. Nature. 2022. PMID: 35585241 Free PMC article.
Breast cancer cells rely on environmental pyruvate to shape the metastatic niche.
Elia I, Rossi M, Stegen S, Broekaert D, Doglioni G, van Gorsel M, Boon R, Escalona-Noguero C, Torrekens S, Verfaillie C, Verbeken E, Carmeliet G, Fendt SM. Elia I, et al. Among authors: doglioni g. Nature. 2019 Apr;568(7750):117-121. doi: 10.1038/s41586-019-0977-x. Epub 2019 Feb 27. Nature. 2019. PMID: 30814728 Free PMC article.
Author Correction: PHGDH heterogeneity potentiates cancer cell dissemination and metastasis.
Rossi M, Altea-Manzano P, Demicco M, Doglioni G, Bornes L, Fukano M, Vandekeere A, Cuadros AM, Fernández-García J, Riera-Domingo C, Jauset C, Planque M, Alkan HF, Nittner D, Zuo D, Broadfield LA, Parik S, Pane AA, Rizzollo F, Rinaldi G, Zhang T, Teoh ST, Aurora AB, Karras P, Vermeire I, Broekaert D, Elsen JV, Knott MML, Orth MF, Demeyer S, Eelen G, Dobrolecki LE, Bassez A, Brussel TV, Sotlar K, Lewis MT, Bartsch H, Wuhrer M, Veelen PV, Carmeliet P, Cools J, Morrison SJ, Marine JC, Lambrechts D, Mazzone M, Hannon GJ, Lunt SY, Grünewald TGP, Park M, Rheenen JV, Fendt SM. Rossi M, et al. Among authors: doglioni g. Nature. 2022 Sep;609(7927):E8. doi: 10.1038/s41586-022-05226-7. Nature. 2022. PMID: 36042336 Free PMC article. No abstract available.
Metabolic Hallmarks of Metastasis Formation.
Elia I, Doglioni G, Fendt SM. Elia I, et al. Among authors: doglioni g. Trends Cell Biol. 2018 Aug;28(8):673-684. doi: 10.1016/j.tcb.2018.04.002. Epub 2018 May 7. Trends Cell Biol. 2018. PMID: 29747903 Review.
Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines.
Boon R, Kumar M, Tricot T, Elia I, Ordovas L, Jacobs F, One J, De Smedt J, Eelen G, Bird M, Roelandt P, Doglioni G, Vriens K, Rossi M, Vazquez MA, Vanwelden T, Chesnais F, El Taghdouini A, Najimi M, Sokal E, Cassiman D, Snoeys J, Monshouwer M, Hu WS, Lange C, Carmeliet P, Fendt SM, Verfaillie CM. Boon R, et al. Among authors: doglioni g. Nat Commun. 2020 Mar 13;11(1):1393. doi: 10.1038/s41467-020-15058-6. Nat Commun. 2020. PMID: 32170132 Free PMC article.
In Vivo Evidence for Serine Biosynthesis-Defined Sensitivity of Lung Metastasis, but Not of Primary Breast Tumors, to mTORC1 Inhibition.
Rinaldi G, Pranzini E, Van Elsen J, Broekaert D, Funk CM, Planque M, Doglioni G, Altea-Manzano P, Rossi M, Geldhof V, Teoh ST, Ross C, Hunter KW, Lunt SY, Grünewald TGP, Fendt SM. Rinaldi G, et al. Among authors: doglioni g. Mol Cell. 2021 Jan 21;81(2):386-397.e7. doi: 10.1016/j.molcel.2020.11.027. Epub 2020 Dec 18. Mol Cell. 2021. PMID: 33340488 Free PMC article.
Pyrvinium Pamoate Induces Death of Triple-Negative Breast Cancer Stem-Like Cells and Reduces Metastases through Effects on Lipid Anabolism.
Dattilo R, Mottini C, Camera E, Lamolinara A, Auslander N, Doglioni G, Muscolini M, Tang W, Planque M, Ercolani C, Buglioni S, Manni I, Trisciuoglio D, Boe A, Grande S, Luciani AM, Iezzi M, Ciliberto G, Ambs S, De Maria R, Fendt SM, Ruppin E, Cardone L. Dattilo R, et al. Among authors: doglioni g. Cancer Res. 2020 Oct 1;80(19):4087-4102. doi: 10.1158/0008-5472.CAN-19-1184. Epub 2020 Jul 23. Cancer Res. 2020. PMID: 32718996 Free PMC article.
12 results