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Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia.
Moder M, Velimezi G, Owusu M, Mazouzi A, Wiedner M, Ferreira da Silva J, Robinson-Garcia L, Schischlik F, Slavkovsky R, Kralovics R, Schuster M, Bock C, Ideker T, Jackson SP, Menche J, Loizou JI. Moder M, et al. Among authors: wiedner m. Nat Commun. 2017 Nov 1;8(1):1238. doi: 10.1038/s41467-017-01439-x. Nat Commun. 2017. PMID: 29089570 Free PMC article.
Map of synthetic rescue interactions for the Fanconi anemia DNA repair pathway identifies USP48.
Velimezi G, Robinson-Garcia L, Muñoz-Martínez F, Wiegant WW, Ferreira da Silva J, Owusu M, Moder M, Wiedner M, Rosenthal SB, Fisch KM, Moffat J, Menche J, van Attikum H, Jackson SP, Loizou JI. Velimezi G, et al. Among authors: wiedner m. Nat Commun. 2018 Jun 11;9(1):2280. doi: 10.1038/s41467-018-04649-z. Nat Commun. 2018. PMID: 29891926 Free PMC article.
A Comprehensive Analysis of the Dynamic Response to Aphidicolin-Mediated Replication Stress Uncovers Targets for ATM and ATMIN.
Mazouzi A, Stukalov A, Müller AC, Chen D, Wiedner M, Prochazkova J, Chiang SC, Schuster M, Breitwieser FP, Pichlmair A, El-Khamisy SF, Bock C, Kralovics R, Colinge J, Bennett KL, Loizou JI. Mazouzi A, et al. Among authors: wiedner m. Cell Rep. 2016 Apr 26;15(4):893-908. doi: 10.1016/j.celrep.2016.03.077. Epub 2016 Apr 14. Cell Rep. 2016. PMID: 27149854 Free article.
Mapping the Human Kinome in Response to DNA Damage.
Owusu M, Bannauer P, Ferreira da Silva J, Mourikis TP, Jones A, Májek P, Caldera M, Wiedner M, Lardeau CH, Mueller AC, Menche J, Kubicek S, Ciccarelli FD, Loizou JI. Owusu M, et al. Among authors: wiedner m. Cell Rep. 2019 Jan 15;26(3):555-563.e6. doi: 10.1016/j.celrep.2018.12.087. Cell Rep. 2019. PMID: 30650350 Free article.
DNA Repair Cofactors ATMIN and NBS1 Are Required to Suppress T Cell Activation.
Prochazkova J, Sakaguchi S, Owusu M, Mazouzi A, Wiedner M, Velimezi G, Moder M, Turchinovich G, Hladik A, Gurnhofer E, Hayday A, Behrens A, Knapp S, Kenner L, Ellmeier W, Loizou JI. Prochazkova J, et al. Among authors: wiedner m. PLoS Genet. 2015 Nov 6;11(11):e1005645. doi: 10.1371/journal.pgen.1005645. eCollection 2015 Nov. PLoS Genet. 2015. PMID: 26544571 Free PMC article.
Klebsiella oxytoca enterotoxins tilimycin and tilivalline have distinct host DNA-damaging and microtubule-stabilizing activities.
Unterhauser K, Pöltl L, Schneditz G, Kienesberger S, Glabonjat RA, Kitsera M, Pletz J, Josa-Prado F, Dornisch E, Lembacher-Fadum C, Roier S, Gorkiewicz G, Lucena D, Barasoain I, Kroutil W, Wiedner M, Loizou JI, Breinbauer R, Díaz JF, Schild S, Högenauer C, Zechner EL. Unterhauser K, et al. Among authors: wiedner m. Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3774-3783. doi: 10.1073/pnas.1819154116. Epub 2019 Feb 11. Proc Natl Acad Sci U S A. 2019. PMID: 30808763 Free PMC article.
Mutational Signatures Driven by Epigenetic Determinants Enable the Stratification of Patients with Gastric Cancer for Therapeutic Intervention.
Buttura JR, Provisor Santos MN, Valieris R, Drummond RD, Defelicibus A, Lima JP, Calsavara VF, Freitas HC, Cordeiro de Lima VC, Fernanda Bartelli T, Wiedner M, Rosales R, Gollob KJ, Loizou J, Dias-Neto E, Nunes DN, da Silva IT. Buttura JR, et al. Among authors: wiedner m. Cancers (Basel). 2021 Jan 27;13(3):490. doi: 10.3390/cancers13030490. Cancers (Basel). 2021. PMID: 33513945 Free PMC article.
49 results