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Bioisosteric Development of Multitarget Nonsteroidal Anti-Inflammatory Drug-Carbonic Anhydrases Inhibitor Hybrids for the Management of Rheumatoid Arthritis.
Bua S, Lucarini L, Micheli L, Menicatti M, Bartolucci G, Selleri S, Di Cesare Mannelli L, Ghelardini C, Masini E, Carta F, Gratteri P, Nocentini A, Supuran CT. Bua S, et al. Among authors: ghelardini c. J Med Chem. 2020 Mar 12;63(5):2325-2342. doi: 10.1021/acs.jmedchem.9b01130. Epub 2019 Nov 15. J Med Chem. 2020. PMID: 31689108
Local anaesthetic activity of beta-caryophyllene.
Ghelardini C, Galeotti N, Di Cesare Mannelli L, Mazzanti G, Bartolini A. Ghelardini C, et al. Farmaco. 2001 May-Jul;56(5-7):387-9. doi: 10.1016/s0014-827x(01)01092-8. Farmaco. 2001. PMID: 11482764
Menthol: a natural analgesic compound.
Galeotti N, Di Cesare Mannelli L, Mazzanti G, Bartolini A, Ghelardini C. Galeotti N, et al. Among authors: ghelardini c. Neurosci Lett. 2002 Apr 12;322(3):145-8. doi: 10.1016/s0304-3940(01)02527-7. Neurosci Lett. 2002. PMID: 11897159
Gi/o proteins: expression for direct activation enquiry.
Di Cesare Mannelli L, Pacini A, Toscano A, Fortini M, Berti D, Ghelardini C, Galeotti N, Baglioni P, Bartolini A. Di Cesare Mannelli L, et al. Among authors: ghelardini c. Protein Expr Purif. 2006 May;47(1):303-10. doi: 10.1016/j.pep.2005.11.005. Epub 2005 Dec 5. Protein Expr Purif. 2006. PMID: 16364655
Structural investigation of the 7-chloro-3-hydroxy-1H-quinazoline-2,4-dione scaffold to obtain AMPA and kainate receptor selective antagonists. Synthesis, pharmacological, and molecular modeling studies.
Colotta V, Catarzi D, Varano F, Lenzi O, Filacchioni G, Costagli C, Galli A, Ghelardini C, Galeotti N, Gratteri P, Sgrignani J, Deflorian F, Moro S. Colotta V, et al. Among authors: ghelardini c. J Med Chem. 2006 Oct 5;49(20):6015-26. doi: 10.1021/jm0604880. J Med Chem. 2006. PMID: 17004715
Novel 3-iodo-8-ethoxypyrazolo[5,1-c][1,2,4]benzotriazine 5-oxide as promising lead for design of alpha5-inverse agonist useful tools for therapy of mnemonic damage.
Guerrini G, Ciciani G, Cambi G, Bruni F, Selleri S, Besnard F, Montali M, Martini C, Ghelardini C, Galeotti N, Costanzo A. Guerrini G, et al. Among authors: ghelardini c. Bioorg Med Chem. 2007 Apr 1;15(7):2573-86. doi: 10.1016/j.bmc.2007.01.053. Epub 2007 Feb 2. Bioorg Med Chem. 2007. PMID: 17306981
489 results