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The antioxidant 2,3-dichloro,5,8-dihydroxy,1,4-naphthoquinone inhibits acetyl-cholinesterase activity and amyloid β42 aggregation: A dual target therapeutic candidate compound for the treatment of Alzheimer's disease.
Biotechnol Appl Biochem. 2020 Nov;67(6):983-990. doi: 10.1002/bab.1870. Epub 2020 Feb 17.
Biotechnol Appl Biochem. 2020.
PMID: 31820491
1,2,4-trihydroxynaphthalene-2-O-β-D-glucopyranoside: A new powerful antioxidant and inhibitor of Aβ42 aggregation isolated from the leaves of Lawsonia inermis.
Dhouafli Z, Ben Jannet H, Mahjoub B, Leri M, Guillard J, Saidani Tounsi M, Stefani M, Hayouni EA.
Dhouafli Z, et al.
Nat Prod Res. 2019 May;33(10):1406-1414. doi: 10.1080/14786419.2017.1419229. Epub 2017 Dec 29.
Nat Prod Res. 2019.
PMID: 29287545
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1,2,4-trihydroxynaphthalene-2-O-β-D-glucopyranoside delays amyloid-β42 aggregation and reduces amyloid cytotoxicity.
Dhouafli Z, Leri M, Bucciantini M, Stefani M, Gadhoumi H, Mahjoub B, Ben Jannet H, Guillard J, Ksouri R, Saidani Tounsi M, Soto C, Hayouni EA.
Dhouafli Z, et al.
Biofactors. 2018 May;44(3):272-280. doi: 10.1002/biof.1422. Epub 2018 Mar 26.
Biofactors. 2018.
PMID: 29582494
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A new purified Lawsoniaside remodels amyloid-β42 fibrillation into a less toxic and non-amyloidogenic pathway.
Dhouafli Z, Leri M, Bucciantini M, Stefani M, Gadhoumi H, Mahjoub B, Ben Jannet H, Guillard J, Tounsi MS, Ksouri R, Hayouni EA.
Dhouafli Z, et al.
Int J Biol Macromol. 2018 Jul 15;114:830-835. doi: 10.1016/j.ijbiomac.2018.04.005. Epub 2018 Apr 4.
Int J Biol Macromol. 2018.
PMID: 29626601
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Inhibition of protein misfolding and aggregation by natural phenolic compounds.
Dhouafli Z, Cuanalo-Contreras K, Hayouni EA, Mays CE, Soto C, Moreno-Gonzalez I.
Dhouafli Z, et al.
Cell Mol Life Sci. 2018 Oct;75(19):3521-3538. doi: 10.1007/s00018-018-2872-2. Epub 2018 Jul 20.
Cell Mol Life Sci. 2018.
PMID: 30030591
Free PMC article.
Review.
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Chemical composition, antimicrobial and antioxidant activities data of three plants from Tunisia region: Erodium glaucophyllum, Erodium hirtum and Erodium guttatum.
Hamza G, Emna BH, Yeddes W, Dhouafli Z, Moufida TS, El Akrem H.
Hamza G, et al. Among authors: dhouafli z.
Data Brief. 2018 Jul 10;19:2352-2355. doi: 10.1016/j.dib.2018.07.005. eCollection 2018 Aug.
Data Brief. 2018.
PMID: 30246100
Free PMC article.
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Biochemical Composition, Antioxidant Capacity and Protective Effects of Three Fermented Plants Beverages on Hepatotoxicity and Nephrotoxicity Induced by Carbon Tetrachloride in Mice.
Gadhoumi H, Dhouafli Z, Yeddes W, Serairi Beji R, Miled K, Trifi M, Chirchi A, Saidani Tounsi M, Hayouni EA.
Gadhoumi H, et al. Among authors: dhouafli z.
Indian J Microbiol. 2024 Mar;64(1):229-243. doi: 10.1007/s12088-023-01172-8. Epub 2023 Dec 26.
Indian J Microbiol. 2024.
PMID: 38468731
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