Berezovska O - Search Results

1

Synapsin 1 promotes Aβ generation via BACE1 modulation.

Maesako M, Zoltowska KM, Berezovska O. Maesako M, et al. Among authors: berezovska o. PLoS One. 2019 Dec 12;14(12):e0226368. doi: 10.1371/journal.pone.0226368. eCollection 2019. PLoS One. 2019. PMID: 31830091 Free PMC article.

2

Notch1 and amyloid precursor protein are competitive substrates for presenilin1-dependent gamma-secretase cleavage.

Berezovska O, Jack C, Deng A, Gastineau N, Rebeck GW, Hyman BT. Berezovska O, et al. J Biol Chem. 2001 Aug 10;276(32):30018-23. doi: 10.1074/jbc.M008268200. Epub 2001 Jun 14. J Biol Chem. 2001. PMID: 11408475 Free article.

3

Acyl-coenzyme A: cholesterol acyltransferase modulates the generation of the amyloid beta-peptide.

Puglielli L, Konopka G, Pack-Chung E, Ingano LA, Berezovska O, Hyman BT, Chang TY, Tanzi RE, Kovacs DM. Puglielli L, et al. Among authors: berezovska o. Nat Cell Biol. 2001 Oct;3(10):905-12. doi: 10.1038/ncb1001-905. Nat Cell Biol. 2001. PMID: 11584272

4

Amyloid precursor protein associates with a nicastrin-dependent docking site on the presenilin 1-gamma-secretase complex in cells demonstrated by fluorescence lifetime imaging.

Berezovska O, Ramdya P, Skoch J, Wolfe MS, Bacskai BJ, Hyman BT. Berezovska O, et al. J Neurosci. 2003 Jun 1;23(11):4560-6. doi: 10.1523/JNEUROSCI.23-11-04560.2003. J Neurosci. 2003. PMID: 12805296 Free PMC article.

5

Notch1 competes with the amyloid precursor protein for gamma-secretase and down-regulates presenilin-1 gene expression.

Lleó A, Berezovska O, Ramdya P, Fukumoto H, Raju S, Shah T, Hyman BT. Lleó A, et al. Among authors: berezovska o. J Biol Chem. 2003 Nov 28;278(48):47370-5. doi: 10.1074/jbc.M308480200. Epub 2003 Sep 5. J Biol Chem. 2003. PMID: 12960155 Free article.

6

Activated Notch1 associates with a presenilin-1/gamma-secretase docking site.

Ramdya P, Skoch J, Bacskai BJ, Hyman BT, Berezovska O. Ramdya P, et al. Among authors: berezovska o. J Neurochem. 2003 Nov;87(4):843-50. doi: 10.1046/j.1471-4159.2003.02030.x. J Neurochem. 2003. PMID: 14622115 Free article.

7

Nonsteroidal anti-inflammatory drugs lower Abeta42 and change presenilin 1 conformation.

Lleó A, Berezovska O, Herl L, Raju S, Deng A, Bacskai BJ, Frosch MP, Irizarry M, Hyman BT. Lleó A, et al. Among authors: berezovska o. Nat Med. 2004 Oct;10(10):1065-6. doi: 10.1038/nm1112. Epub 2004 Sep 26. Nat Med. 2004. PMID: 15448688

8

Familial Alzheimer's disease presenilin 1 mutations cause alterations in the conformation of presenilin and interactions with amyloid precursor protein.

Berezovska O, Lleo A, Herl LD, Frosch MP, Stern EA, Bacskai BJ, Hyman BT. Berezovska O, et al. J Neurosci. 2005 Mar 16;25(11):3009-17. doi: 10.1523/JNEUROSCI.0364-05.2005. J Neurosci. 2005. PMID: 15772361 Free PMC article.

9

Low density lipoprotein receptor-related protein (LRP) interacts with presenilin 1 and is a competitive substrate of the amyloid precursor protein (APP) for gamma-secretase.

Lleó A, Waldron E, von Arnim CA, Herl L, Tangredi MM, Peltan ID, Strickland DK, Koo EH, Hyman BT, Pietrzik CU, Berezovska O. Lleó A, et al. Among authors: berezovska o. J Biol Chem. 2005 Jul 22;280(29):27303-9. doi: 10.1074/jbc.M413969200. Epub 2005 May 25. J Biol Chem. 2005. PMID: 15917251 Free article.

10

APP substitutions V715F and L720P alter PS1 conformation and differentially affect Abeta and AICD generation.

Tesco G, Ginestroni A, Hiltunen M, Kim M, Dolios G, Hyman BT, Wang R, Berezovska O, Tanzi RE. Tesco G, et al. Among authors: berezovska o. J Neurochem. 2005 Oct;95(2):446-56. doi: 10.1111/j.1471-4159.2005.03381.x. Epub 2005 Aug 8. J Neurochem. 2005. PMID: 16086682 Free article.

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