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Ivermectin inhibits HSP27 and potentiates efficacy of oncogene targeting in tumor models.
Nappi L, Aguda AH, Nakouzi NA, Lelj-Garolla B, Beraldi E, Lallous N, Thi M, Moore S, Fazli L, Battsogt D, Stief S, Ban F, Nguyen NT, Saxena N, Dueva E, Zhang F, Yamazaki T, Zoubeidi A, Cherkasov A, Brayer GD, Gleave M. Nappi L, et al. Among authors: nguyen nt. J Clin Invest. 2020 Feb 3;130(2):699-714. doi: 10.1172/JCI130819. J Clin Invest. 2020. PMID: 31845908 Free PMC article.
Structural basis of collagen fiber degradation by cathepsin K.
Aguda AH, Panwar P, Du X, Nguyen NT, Brayer GD, Brömme D. Aguda AH, et al. Among authors: nguyen nt. Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):17474-9. doi: 10.1073/pnas.1414126111. Epub 2014 Nov 24. Proc Natl Acad Sci U S A. 2014. PMID: 25422423 Free PMC article.
Potent Human α-Amylase Inhibition by the β-Defensin-like Protein Helianthamide.
Tysoe C, Williams LK, Keyzers R, Nguyen NT, Tarling C, Wicki J, Goddard-Borger ED, Aguda AH, Perry S, Foster LJ, Andersen RJ, Brayer GD, Withers SG. Tysoe C, et al. Among authors: nguyen nt. ACS Cent Sci. 2016 Mar 23;2(3):154-161. doi: 10.1021/acscentsci.5b00399. Epub 2016 Feb 26. ACS Cent Sci. 2016. PMID: 27066537 Free PMC article.
The amylase inhibitor montbretin A reveals a new glycosidase inhibition motif.
Williams LK, Zhang X, Caner S, Tysoe C, Nguyen NT, Wicki J, Williams DE, Coleman J, McNeill JH, Yuen V, Andersen RJ, Withers SG, Brayer GD. Williams LK, et al. Among authors: nguyen nt. Nat Chem Biol. 2015 Sep;11(9):691-6. doi: 10.1038/nchembio.1865. Epub 2015 Jul 27. Nat Chem Biol. 2015. PMID: 26214255
1,603 results