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Recent progress in understanding Alzheimer's β-amyloid structures.
Fändrich M, Schmidt M, Grigorieff N. Fändrich M, et al. Among authors: schmidt m. Trends Biochem Sci. 2011 Jun;36(6):338-45. doi: 10.1016/j.tibs.2011.02.002. Epub 2011 Mar 14. Trends Biochem Sci. 2011. PMID: 21411326 Free PMC article. Review.
Peptide dimer structure in an Aβ(1-42) fibril visualized with cryo-EM.
Schmidt M, Rohou A, Lasker K, Yadav JK, Schiene-Fischer C, Fändrich M, Grigorieff N. Schmidt M, et al. Proc Natl Acad Sci U S A. 2015 Sep 22;112(38):11858-63. doi: 10.1073/pnas.1503455112. Epub 2015 Sep 8. Proc Natl Acad Sci U S A. 2015. PMID: 26351699 Free PMC article.
Polymorphism of Amyloid Fibrils In Vivo.
Annamalai K, Gührs KH, Koehler R, Schmidt M, Michel H, Loos C, Gaffney PM, Sigurdson CJ, Hegenbart U, Schönland S, Fändrich M. Annamalai K, et al. Among authors: schmidt m. Angew Chem Int Ed Engl. 2016 Apr 4;55(15):4822-5. doi: 10.1002/anie.201511524. Epub 2016 Mar 8. Angew Chem Int Ed Engl. 2016. PMID: 26954430 Free PMC article.
Electron tomography reveals the fibril structure and lipid interactions in amyloid deposits.
Kollmer M, Meinhardt K, Haupt C, Liberta F, Wulff M, Linder J, Handl L, Heinrich L, Loos C, Schmidt M, Syrovets T, Simmet T, Westermark P, Westermark GT, Horn U, Schmidt V, Walther P, Fändrich M. Kollmer M, et al. Among authors: schmidt m, schmidt v. Proc Natl Acad Sci U S A. 2016 May 17;113(20):5604-9. doi: 10.1073/pnas.1523496113. Epub 2016 May 2. Proc Natl Acad Sci U S A. 2016. PMID: 27140609 Free PMC article.
Common Fibril Structures Imply Systemically Conserved Protein Misfolding Pathways In Vivo.
Annamalai K, Liberta F, Vielberg MT, Close W, Lilie H, Gührs KH, Schierhorn A, Koehler R, Schmidt A, Haupt C, Hegenbart U, Schönland S, Schmidt M, Groll M, Fändrich M. Annamalai K, et al. Among authors: schmidt m, schmidt a. Angew Chem Int Ed Engl. 2017 Jun 19;56(26):7510-7514. doi: 10.1002/anie.201701761. Epub 2017 May 23. Angew Chem Int Ed Engl. 2017. PMID: 28544119
Physical basis of amyloid fibril polymorphism.
Close W, Neumann M, Schmidt A, Hora M, Annamalai K, Schmidt M, Reif B, Schmidt V, Grigorieff N, Fändrich M. Close W, et al. Among authors: schmidt m, schmidt a, schmidt v. Nat Commun. 2018 Feb 16;9(1):699. doi: 10.1038/s41467-018-03164-5. Nat Commun. 2018. PMID: 29453354 Free PMC article.
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