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Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer's disease.
Gate D, Saligrama N, Leventhal O, Yang AC, Unger MS, Middeldorp J, Chen K, Lehallier B, Channappa D, De Los Santos MB, McBride A, Pluvinage J, Elahi F, Tam GK, Kim Y, Greicius M, Wagner AD, Aigner L, Galasko DR, Davis MM, Wyss-Coray T. Gate D, et al. Among authors: middeldorp j. Nature. 2020 Jan;577(7790):399-404. doi: 10.1038/s41586-019-1895-7. Epub 2020 Jan 8. Nature. 2020. PMID: 31915375 Free PMC article.
Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice.
Villeda SA, Plambeck KE, Middeldorp J, Castellano JM, Mosher KI, Luo J, Smith LK, Bieri G, Lin K, Berdnik D, Wabl R, Udeochu J, Wheatley EG, Zou B, Simmons DA, Xie XS, Longo FM, Wyss-Coray T. Villeda SA, et al. Among authors: middeldorp j. Nat Med. 2014 Jun;20(6):659-63. doi: 10.1038/nm.3569. Epub 2014 May 4. Nat Med. 2014. PMID: 24793238 Free PMC article.
Preclinical Assessment of Young Blood Plasma for Alzheimer Disease.
Middeldorp J, Lehallier B, Villeda SA, Miedema SS, Evans E, Czirr E, Zhang H, Luo J, Stan T, Mosher KI, Masliah E, Wyss-Coray T. Middeldorp J, et al. JAMA Neurol. 2016 Nov 1;73(11):1325-1333. doi: 10.1001/jamaneurol.2016.3185. JAMA Neurol. 2016. PMID: 27598869 Free PMC article.
Crossing borders in Alzheimer's disease: A T cell's perspective.
van Olst L, Coenen L, Nieuwland JM, Rodriguez-Mogeda C, de Wit NM, Kamermans A, Middeldorp J, de Vries HE. van Olst L, et al. Among authors: middeldorp j. Adv Drug Deliv Rev. 2022 Sep;188:114398. doi: 10.1016/j.addr.2022.114398. Epub 2022 Jun 30. Adv Drug Deliv Rev. 2022. PMID: 35780907 Free article. Review.
Differential compartmentalization of myeloid cell phenotypes and responses towards the CNS in Alzheimer's disease.
Fernández Zapata C, Giacomello G, Spruth EJ, Middeldorp J, Gallaccio G, Dehlinger A, Dames C, Leman JKH, van Dijk RE, Meisel A, Schlickeiser S, Kunkel D, Hol EM, Paul F, Parr MK, Priller J, Böttcher C. Fernández Zapata C, et al. Among authors: middeldorp j. Nat Commun. 2022 Nov 23;13(1):7210. doi: 10.1038/s41467-022-34719-2. Nat Commun. 2022. PMID: 36418303 Free PMC article.
Denser brain capillary network with preserved pericytes in Alzheimer's disease.
Fernandez-Klett F, Brandt L, Fernández-Zapata C, Abuelnor B, Middeldorp J, Sluijs JA, Curtis M, Faull R, Harris LW, Bahn S, Hol EM, Priller J. Fernandez-Klett F, et al. Among authors: middeldorp j. Brain Pathol. 2020 Nov;30(6):1071-1086. doi: 10.1111/bpa.12897. Epub 2020 Sep 29. Brain Pathol. 2020. PMID: 32876357 Free PMC article.
The adult human subventricular zone: partial ependymal coverage and proliferative capacity of cerebrospinal fluid.
de Sonnaville SFAM, van Strien ME, Middeldorp J, Sluijs JA, van den Berge SA, Moeton M, Donega V, van Berkel A, Deering T, De Filippis L, Vescovi AL, Aronica E, Glass R, van de Berg WDJ, Swaab DF, Robe PA, Hol EM. de Sonnaville SFAM, et al. Among authors: middeldorp j. Brain Commun. 2020 Oct 13;2(2):fcaa150. doi: 10.1093/braincomms/fcaa150. eCollection 2020. Brain Commun. 2020. PMID: 33376983 Free PMC article.
433 results