Shia KS - Search Results

1

Unique Sulfur-Aromatic Interactions Contribute to the Binding of Potent Imidazothiazole Indoleamine 2,3-Dioxygenase Inhibitors.

Peng YH, Liao FY, Tseng CT, Kuppusamy R, Li AS, Chen CH, Fan YS, Wang SY, Wu MH, Hsueh CC, Chang JY, Lee LC, Shih C, Shia KS, Yeh TK, Hung MS, Kuo CC, Song JS, Wu SY, Ueng SH. Peng YH, et al. Among authors: shia ks. J Med Chem. 2020 Feb 27;63(4):1642-1659. doi: 10.1021/acs.jmedchem.9b01549. Epub 2020 Feb 10. J Med Chem. 2020. PMID: 31961685

2

Design, synthesis, and structure-activity relationship of pyridyl imidazolidinones: a novel class of potent and selective human enterovirus 71 inhibitors.

Shia KS, Li WT, Chang CM, Hsu MC, Chern JH, Leong MK, Tseng SN, Lee CC, Lee YC, Chen SJ, Peng KC, Tseng HY, Chang YL, Tai CL, Shih SR. Shia KS, et al. J Med Chem. 2002 Apr 11;45(8):1644-55. doi: 10.1021/jm010536a. J Med Chem. 2002. PMID: 11931618

3

Design, synthesis, and structure-activity relationships of pyrazolo[3,4-d]pyrimidines: a novel class of potent enterovirus inhibitors.

Chern JH, Shia KS, Hsu TA, Tai CL, Lee CC, Lee YC, Chang CS, Tseng SN, Shih SR. Chern JH, et al. Among authors: shia ks. Bioorg Med Chem Lett. 2004 May 17;14(10):2519-25. doi: 10.1016/j.bmcl.2004.02.092. Bioorg Med Chem Lett. 2004. PMID: 15109643

4

Selective human enterovirus and rhinovirus inhibitors: An overview of capsid-binding and protease-inhibiting molecules.

Shih SR, Chen SJ, Hakimelahi GH, Liu HJ, Tseng CT, Shia KS. Shih SR, et al. Among authors: shia ks. Med Res Rev. 2004 Jul;24(4):449-74. doi: 10.1002/med.10067. Med Res Rev. 2004. PMID: 15170592 Free PMC article. Review.

5

Synthesis and antienteroviral activity of a series of novel, oxime ether-containing pyridyl imidazolidinones.

Chern JH, Lee CC, Chang CS, Lee YC, Tai CL, Lin YT, Shia KS, Lee CY, Shih SR. Chern JH, et al. Among authors: shia ks. Bioorg Med Chem Lett. 2004 Oct 18;14(20):5051-6. doi: 10.1016/j.bmcl.2004.07.084. Bioorg Med Chem Lett. 2004. PMID: 15380197

6

Design, synthesis, and biological evaluation of novel alkenylthiophenes as potent and selective CB1 cannabinoid receptor antagonists.

Tai CL, Hung MS, Pawar VD, Tseng SL, Song JS, Hsieh WP, Chiu HH, Wu HC, Hsieh MT, Kuo CW, Hsieh CC, Tsao JP, Chao YS, Shia KS. Tai CL, et al. Among authors: shia ks. Org Biomol Chem. 2008 Feb 7;6(3):447-50. doi: 10.1039/b716434c. Epub 2007 Dec 10. Org Biomol Chem. 2008. PMID: 18219411

7

Bioisosteric replacement of the pyrazole 5-aryl moiety of N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A). A novel series of alkynylthiophenes as potent and selective cannabinoid-1 receptor antagonists.

Tseng SL, Hung MS, Chang CP, Song JS, Tai CL, Chiu HH, Hsieh WP, Lin Y, Chung WL, Kuo CW, Wu CH, Chu CM, Tung YS, Chao YS, Shia KS. Tseng SL, et al. Among authors: shia ks. J Med Chem. 2008 Sep 11;51(17):5397-412. doi: 10.1021/jm800066v. Epub 2008 Aug 20. J Med Chem. 2008. PMID: 18712856

8

Bioisosteric replacement of the pyrazole 3-carboxamide moiety of rimonabant. A novel series of oxadiazoles as CB1 cannabinoid receptor antagonists.

Chu CM, Hung MS, Hsieh MT, Kuo CW, Suja TD, Song JS, Chiu HH, Chao YS, Shia KS. Chu CM, et al. Among authors: shia ks. Org Biomol Chem. 2008 Sep 21;6(18):3399-407. doi: 10.1039/b807648k. Epub 2008 Jul 23. Org Biomol Chem. 2008. PMID: 18802648

9

Discovery of 2-[5-(4-chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl-1H-pyrazol-3-yl]-1,5,5-trimethyl-1,5-dihydro-imidazol-4-thione (BPR-890) via an active metabolite. A novel, potent and selective cannabinoid-1 receptor inverse agonist with high antiobesity efficacy in DIO mice.

Wu CH, Hung MS, Song JS, Yeh TK, Chou MC, Chu CM, Jan JJ, Hsieh MT, Tseng SL, Chang CP, Hsieh WP, Lin Y, Yeh YN, Chung WL, Kuo CW, Lin CY, Shy HS, Chao YS, Shia KS. Wu CH, et al. Among authors: shia ks. J Med Chem. 2009 Jul 23;52(14):4496-510. doi: 10.1021/jm900471u. J Med Chem. 2009. PMID: 19530697

10

Biphasic suppression of appetite by cannabinoid CB1 receptor antagonists with distinct functional activities.

Lin Y, Shia KS, Hsiao WC, Hsieh WP, Yeh TK, Tseng SL, Hsu CY, Chao YS, Hung MS. Lin Y, et al. Among authors: shia ks. Pharmacol Res. 2010 Oct;62(4):337-43. doi: 10.1016/j.phrs.2010.06.001. Epub 2010 Jun 8. Pharmacol Res. 2010. PMID: 20554040

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