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Selective deletion of interleukin-1 alpha in microglia regulates neuronal responses and neurorepair processes after experimental ischemic stroke.
Lemarchand E, Grayston A, Wong R, Rogers M, Ouvrier B, Llewellyn B, Webb F, Lénárt N, Denes A, Brough D, Allan SM, Bix G, Pinteaux E. Lemarchand E, et al. Among authors: brough d. bioRxiv [Preprint]. 2024 Mar 25:2024.02.16.580635. doi: 10.1101/2024.02.16.580635. bioRxiv. 2024. PMID: 38585834 Free PMC article. Preprint.
The Application of Knowledge Engineering via the Use of a Biomimetic Digital Twin Ecosystem, Phenotype-Driven Variant Analysis, and Exome Sequencing to Understand the Molecular Mechanisms of Disease.
Kearns WG, Stamoulis JG, Glick J, Baisch L, Benner A, Brough D, Du L, Wilson B, Kearns L, Ng N, Seshan M, Anchan R. Kearns WG, et al. Among authors: brough d. J Mol Diagn. 2024 Mar 29:S1525-1578(24)00062-X. doi: 10.1016/j.jmoldx.2024.03.004. Online ahead of print. J Mol Diagn. 2024. PMID: 38556123 Free article.
Brazilin is a natural product inhibitor of the NLRP3 inflammasome.
McMahon E, El-Sayed S, Green J, Hoyle C, FitzPatrick L, Jones EV, Corrie E, Kelly RL, Challinor M, Freeman S, Bryce RA, Lawrence CB, Brough D, Kasher PR. McMahon E, et al. Among authors: brough d. iScience. 2024 Jan 19;27(2):108968. doi: 10.1016/j.isci.2024.108968. eCollection 2024 Feb 16. iScience. 2024. PMID: 38327788 Free PMC article.
The tumor microenvironment state associates with response to HPV therapeutic vaccination in patients with respiratory papillomatosis.
Norberg SM, Bai K, Sievers C, Robbins Y, Friedman J, Yang X, Kenyon M, Ward E, Schlom J, Gulley J, Lankford A, Semnani R, Sabzevari H, Brough DE, Allen CT. Norberg SM, et al. Among authors: brough de. Sci Transl Med. 2023 Oct 25;15(719):eadj0740. doi: 10.1126/scitranslmed.adj0740. Epub 2023 Oct 25. Sci Transl Med. 2023. PMID: 37878675
228 results