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Discovery and Characterization of 2,5-Substituted Benzoic Acid Dual Inhibitors of the Anti-apoptotic Mcl-1 and Bfl-1 Proteins.
Kump KJ, Miao L, Mady ASA, Ansari NH, Shrestha UK, Yang Y, Pal M, Liao C, Perdih A, Abulwerdi FA, Chinnaswamy K, Meagher JL, Carlson JM, Khanna M, Stuckey JA, Nikolovska-Coleska Z. Kump KJ, et al. Among authors: liao c. J Med Chem. 2020 Mar 12;63(5):2489-2510. doi: 10.1021/acs.jmedchem.9b01442. Epub 2020 Feb 14. J Med Chem. 2020. PMID: 31971799 Free PMC article.
Inhibitors of the anti-apoptotic Bcl-2 proteins: a patent review.
Bajwa N, Liao C, Nikolovska-Coleska Z. Bajwa N, et al. Among authors: liao c. Expert Opin Ther Pat. 2012 Jan;22(1):37-55. doi: 10.1517/13543776.2012.644274. Epub 2011 Dec 23. Expert Opin Ther Pat. 2012. PMID: 22195752 Free PMC article. Review.
A novel small-molecule inhibitor of mcl-1 blocks pancreatic cancer growth in vitro and in vivo.
Abulwerdi F, Liao C, Liu M, Azmi AS, Aboukameel A, Mady AS, Gulappa T, Cierpicki T, Owens S, Zhang T, Sun D, Stuckey JA, Mohammad RM, Nikolovska-Coleska Z. Abulwerdi F, et al. Among authors: liao c. Mol Cancer Ther. 2014 Mar;13(3):565-75. doi: 10.1158/1535-7163.MCT-12-0767. Epub 2013 Sep 9. Mol Cancer Ther. 2014. PMID: 24019208 Free PMC article.
3-Substituted-N-(4-hydroxynaphthalen-1-yl)arylsulfonamides as a novel class of selective Mcl-1 inhibitors: structure-based design, synthesis, SAR, and biological evaluation.
Abulwerdi FA, Liao C, Mady AS, Gavin J, Shen C, Cierpicki T, Stuckey JA, Showalter HD, Nikolovska-Coleska Z. Abulwerdi FA, et al. Among authors: liao c. J Med Chem. 2014 May 22;57(10):4111-33. doi: 10.1021/jm500010b. Epub 2014 May 7. J Med Chem. 2014. PMID: 24749893 Free PMC article.
7,007 results