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137 results

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Page 1
Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold.
Vredevoogd DW, Kuilman T, Ligtenberg MA, Boshuizen J, Stecker KE, de Bruijn B, Krijgsman O, Huang X, Kenski JCN, Lacroix R, Mezzadra R, Gomez-Eerland R, Yildiz M, Dagidir I, Apriamashvili G, Zandhuis N, van der Noort V, Visser NL, Blank CU, Altelaar M, Schumacher TN, Peeper DS. Vredevoogd DW, et al. Among authors: peeper ds. Cell. 2020 Jan 23;180(2):404-405. doi: 10.1016/j.cell.2020.01.005. Cell. 2020. PMID: 31978349 Free article. No abstract available.
Parallel in vivo and in vitro melanoma RNAi dropout screens reveal synthetic lethality between hypoxia and DNA damage response inhibition.
Possik PA, Müller J, Gerlach C, Kenski JC, Huang X, Shahrabi A, Krijgsman O, Song JY, Smit MA, Gerritsen B, Lieftink C, Kemper K, Michaut M, Beijersbergen RL, Wessels L, Schumacher TN, Peeper DS. Possik PA, et al. Among authors: peeper ds. Cell Rep. 2014 Nov 20;9(4):1375-86. doi: 10.1016/j.celrep.2014.10.024. Epub 2014 Nov 6. Cell Rep. 2014. PMID: 25456132 Free article.
Detailed imaging and genetic analysis reveal a secondary BRAF(L505H) resistance mutation and extensive intrapatient heterogeneity in metastatic BRAF mutant melanoma patients treated with vemurafenib.
Hoogstraat M, Gadellaa-van Hooijdonk CG, Ubink I, Besselink NJ, Pieterse M, Veldhuis W, van Stralen M, Meijer EF, Willems SM, Hadders MA, Kuilman T, Krijgsman O, Peeper DS, Koudijs MJ, Cuppen E, Voest EE, Lolkema MP. Hoogstraat M, et al. Among authors: peeper ds. Pigment Cell Melanoma Res. 2015 May;28(3):318-23. doi: 10.1111/pcmr.12347. Epub 2015 Jan 7. Pigment Cell Melanoma Res. 2015. PMID: 25515853
MITF: More Interesting Traits, Folks!
Kemper K, Krijgsman O, Peeper DS. Kemper K, et al. Among authors: peeper ds. Pigment Cell Melanoma Res. 2016 May;29(3):263-5. doi: 10.1111/pcmr.12476. Epub 2016 Mar 31. Pigment Cell Melanoma Res. 2016. PMID: 26999069 No abstract available.
BRAF(V600E) Kinase Domain Duplication Identified in Therapy-Refractory Melanoma Patient-Derived Xenografts.
Kemper K, Krijgsman O, Kong X, Cornelissen-Steijger P, Shahrabi A, Weeber F, van der Velden DL, Bleijerveld OB, Kuilman T, Kluin RJC, Sun C, Voest EE, Ju YS, Schumacher TNM, Altelaar AFM, McDermott U, Adams DJ, Blank CU, Haanen JB, Peeper DS. Kemper K, et al. Among authors: peeper ds. Cell Rep. 2016 Jun 28;16(1):263-277. doi: 10.1016/j.celrep.2016.05.064. Epub 2016 Jun 16. Cell Rep. 2016. PMID: 27320919 Free PMC article.
Phenotypic diversity drives paracrine drug tolerance.
Kuilman T, Peeper DS. Kuilman T, et al. Among authors: peeper ds. EMBO Mol Med. 2017 Aug;9(8):987-989. doi: 10.15252/emmm.201707956. EMBO Mol Med. 2017. PMID: 28694322 Free PMC article.
Cancer drug addiction is relayed by an ERK2-dependent phenotype switch.
Kong X, Kuilman T, Shahrabi A, Boshuizen J, Kemper K, Song JY, Niessen HWM, Rozeman EA, Geukes Foppen MH, Blank CU, Peeper DS. Kong X, et al. Among authors: peeper ds. Nature. 2017 Oct 12;550(7675):270-274. doi: 10.1038/nature24037. Epub 2017 Oct 4. Nature. 2017. PMID: 28976960 Free PMC article.
137 results