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Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold.
Vredevoogd DW, Kuilman T, Ligtenberg MA, Boshuizen J, Stecker KE, de Bruijn B, Krijgsman O, Huang X, Kenski JCN, Lacroix R, Mezzadra R, Gomez-Eerland R, Yildiz M, Dagidir I, Apriamashvili G, Zandhuis N, van der Noort V, Visser NL, Blank CU, Altelaar M, Schumacher TN, Peeper DS. Vredevoogd DW, et al. Among authors: schumacher tn. Cell. 2020 Jan 23;180(2):404-405. doi: 10.1016/j.cell.2020.01.005. Cell. 2020. PMID: 31978349 Free article. No abstract available.
Combination of targeted therapy and immunotherapy in melanoma.
Blank CU, Hooijkaas AI, Haanen JB, Schumacher TN. Blank CU, et al. Among authors: schumacher tn. Cancer Immunol Immunother. 2011 Oct;60(10):1359-71. doi: 10.1007/s00262-011-1079-2. Epub 2011 Aug 17. Cancer Immunol Immunother. 2011. PMID: 21847631 Free PMC article. Review.
TCR repertoires of intratumoral T-cell subsets.
Linnemann C, Mezzadra R, Schumacher TN. Linnemann C, et al. Among authors: schumacher tn. Immunol Rev. 2014 Jan;257(1):72-82. doi: 10.1111/imr.12140. Immunol Rev. 2014. PMID: 24329790 Review.
Parallel in vivo and in vitro melanoma RNAi dropout screens reveal synthetic lethality between hypoxia and DNA damage response inhibition.
Possik PA, Müller J, Gerlach C, Kenski JC, Huang X, Shahrabi A, Krijgsman O, Song JY, Smit MA, Gerritsen B, Lieftink C, Kemper K, Michaut M, Beijersbergen RL, Wessels L, Schumacher TN, Peeper DS. Possik PA, et al. Among authors: schumacher tn. Cell Rep. 2014 Nov 20;9(4):1375-86. doi: 10.1016/j.celrep.2014.10.024. Epub 2014 Nov 6. Cell Rep. 2014. PMID: 25456132 Free article.
CANCER IMMUNOLOGY. The "cancer immunogram".
Blank CU, Haanen JB, Ribas A, Schumacher TN. Blank CU, et al. Among authors: schumacher tn. Science. 2016 May 6;352(6286):658-60. doi: 10.1126/science.aaf2834. Science. 2016. PMID: 27151852 Free article. No abstract available.
BRAF(V600E) Kinase Domain Duplication Identified in Therapy-Refractory Melanoma Patient-Derived Xenografts.
Kemper K, Krijgsman O, Kong X, Cornelissen-Steijger P, Shahrabi A, Weeber F, van der Velden DL, Bleijerveld OB, Kuilman T, Kluin RJC, Sun C, Voest EE, Ju YS, Schumacher TNM, Altelaar AFM, McDermott U, Adams DJ, Blank CU, Haanen JB, Peeper DS. Kemper K, et al. Cell Rep. 2016 Jun 28;16(1):263-277. doi: 10.1016/j.celrep.2016.05.064. Epub 2016 Jun 16. Cell Rep. 2016. PMID: 27320919 Free PMC article.
Regulation and Function of the PD-L1 Checkpoint.
Sun C, Mezzadra R, Schumacher TN. Sun C, et al. Among authors: schumacher tn. Immunity. 2018 Mar 20;48(3):434-452. doi: 10.1016/j.immuni.2018.03.014. Immunity. 2018. PMID: 29562194 Free PMC article. Review.
SLFN11 can sensitize tumor cells towards IFN-γ-mediated T cell killing.
Mezzadra R, de Bruijn M, Jae LT, Gomez-Eerland R, Duursma A, Scheeren FA, Brummelkamp TR, Schumacher TN. Mezzadra R, et al. Among authors: schumacher tn. PLoS One. 2019 Feb 12;14(2):e0212053. doi: 10.1371/journal.pone.0212053. eCollection 2019. PLoS One. 2019. PMID: 30753225 Free PMC article.
316 results