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IgA subclasses have different effector functions associated with distinct glycosylation profiles.
Steffen U, Koeleman CA, Sokolova MV, Bang H, Kleyer A, Rech J, Unterweger H, Schicht M, Garreis F, Hahn J, Andes FT, Hartmann F, Hahn M, Mahajan A, Paulsen F, Hoffmann M, Lochnit G, Muñoz LE, Wuhrer M, Falck D, Herrmann M, Schett G. Steffen U, et al. Nat Commun. 2020 Jan 8;11(1):120. doi: 10.1038/s41467-019-13992-8. Nat Commun. 2020. PMID: 31913287 Free PMC article.
Ethanol consumption inhibits TFH cell responses and the development of autoimmune arthritis.
Azizov V, Dietel K, Steffen F, Dürholz K, Meidenbauer J, Lucas S, Frech M, Omata Y, Tajik N, Knipfer L, Kolenbrander A, Seubert S, Lapuente D, Sokolova MV, Hofmann J, Tenbusch M, Ramming A, Steffen U, Nimmerjahn F, Linker R, Wirtz S, Herrmann M, Temchura V, Sarter K, Schett G, Zaiss MM. Azizov V, et al. Among authors: steffen u, steffen f. Nat Commun. 2020 Apr 24;11(1):1998. doi: 10.1038/s41467-020-15855-z. Nat Commun. 2020. PMID: 32332730 Free PMC article.
Osteocyte necrosis triggers osteoclast-mediated bone loss through macrophage-inducible C-type lectin.
Andreev D, Liu M, Weidner D, Kachler K, Faas M, Grüneboom A, Schlötzer-Schrehardt U, Muñoz LE, Steffen U, Grötsch B, Killy B, Krönke G, Luebke AM, Niemeier A, Wehrhan F, Lang R, Schett G, Bozec A. Andreev D, et al. Among authors: steffen u. J Clin Invest. 2020 Sep 1;130(9):4811-4830. doi: 10.1172/JCI134214. J Clin Invest. 2020. PMID: 32773408 Free PMC article.
A crucial role for Jagunal homolog 1 in humoral immunity and antibody glycosylation in mice and humans.
Hagelkruys A, Wirnsberger G, Stadlmann J, Wöhner M, Horrer M, Vilagos B, Jonsson G, Kogler M, Tortola L, Novatchkova M, Bönelt P, Hoffmann D, Koglgruber R, Steffen U, Schett G, Busslinger M, Bergthaler A, Klein C, Penninger JM. Hagelkruys A, et al. Among authors: steffen u. J Exp Med. 2021 Jan 4;218(1):e20200559. doi: 10.1084/jem.20200559. J Exp Med. 2021. PMID: 32930709 Free PMC article.
39 results