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Page 1
Effect of photobiomodulation in the balance between effector and regulatory T cells in an experimental model of COPD.
de Brito AA, Herculano KZ, de Alvarenga-Nascimento CR, Estefano-Alves C, Duran CCG, Marcos RL, Silva Junior JA, Chavantes MC, Zamuner SR, Aimbire F, Lladó-Pelfort L, Gubern A, Fàbrega A, da Palma RK, Ligeiro de Oliveira AP. de Brito AA, et al. Front Med (Lausanne). 2024 Jun 5;11:1347517. doi: 10.3389/fmed.2024.1347517. eCollection 2024. Front Med (Lausanne). 2024. PMID: 38903812 Free PMC article.

One-way ANOVA followed by NewmanKeuls test were used for statistical analysis with significance levels adjusted to 5% (p < 0.05). RESULTS: This result showed that PBM improves COPD symptomatology, reducing the number of inflammatory cells (macrophages, neutrophils and l

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One-way ANOVA followed by NewmanKeuls test were used for statistical analysis with significance levels adjusted to 5% (p < 0.05).

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3D chromatin remodelling in the germ line modulates genome evolutionary plasticity.
Álvarez-González L, Burden F, Doddamani D, Malinverni R, Leach E, Marín-García C, Marín-Gual L, Gubern A, Vara C, Paytuví-Gallart A, Buschbeck M, Ellis PJI, Farré M, Ruiz-Herrera A. Álvarez-González L, et al. Nat Commun. 2022 May 11;13(1):2608. doi: 10.1038/s41467-022-30296-6. Nat Commun. 2022. PMID: 35546158 Free PMC article.
Impact of artificial intelligence support on accuracy and reading time in breast tomosynthesis image interpretation: a multi-reader multi-case study.
van Winkel SL, Rodríguez-Ruiz A, Appelman L, Gubern-Mérida A, Karssemeijer N, Teuwen J, Wanders AJT, Sechopoulos I, Mann RM. van Winkel SL, et al. Eur Radiol. 2021 Nov;31(11):8682-8691. doi: 10.1007/s00330-021-07992-w. Epub 2021 May 4. Eur Radiol. 2021. PMID: 33948701 Free PMC article.

RESULTS: On average, the AUC was higher using AI support (0.863 vs 0.833; p = 0.0025). Using AI support, reading time per DBT exam was reduced (p < 0.001) from 41 (95% CI = 39-42 s) to 36 s (95% CI = 35- 37 s). The AUC of the stand-alone AI system was non-inferio

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RESULTS: On average, the AUC was higher using AI support (0.863 vs 0.833; p = 0.0025). Using AI support, reading time per DBT exam wa …
Intracranial Self-Stimulation Modulates Levels of SIRT1 Protein and Neural Plasticity-Related microRNAs.
Puig-Parnau I, Garcia-Brito S, Faghihi N, Gubern C, Aldavert-Vera L, Segura-Torres P, Huguet G, Kádár E. Puig-Parnau I, et al. Mol Neurobiol. 2020 Jun;57(6):2551-2562. doi: 10.1007/s12035-020-01901-w. Epub 2020 Mar 26. Mol Neurobiol. 2020. PMID: 32219698
Expression of miR-132-3p, miR-181c-5p, miR-495-3p, and SIRT1 protein was upregulated in DG of ICSS rats (P < 0.05). None of the analyzed molecules was regulated in CA3, while miR-132-3p was also increased in CA1 (P = 0.011) and serum (P = 0.048). ...

Expression of miR-132-3p, miR-181c-5p, miR-495-3p, and SIRT1 protein was upregulated in DG of ICSS rats (P < 0.05). None of the an

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Low Levels of Caveolin-1 Predict Symptomatic Bleeding After Thrombolytic Therapy in Patients With Acute Ischemic Stroke.
Castellanos M, van Eendenburg C, Gubern C, Kádár E, Huguet G, Puig J, Sobrino T, Blasco G, Serena J, Sánchez JM. Castellanos M, et al. Stroke. 2018 Jun;49(6):1525-1527. doi: 10.1161/STROKEAHA.118.020683. Epub 2018 Apr 30. Stroke. 2018. PMID: 29712879
RESULTS: Baseline caveolin-1 levels were higher in patients than controls (0.24 [0.17-0.40] versus 0.07 [0.0-0.20] ng/mL; P<0.000). Twenty six (19.5%) patients had HT, which was symptomatic in 7 (5.3%). Patients with parenchymal hemorrhage-2 and sHT had lower baseline c …
RESULTS: Baseline caveolin-1 levels were higher in patients than controls (0.24 [0.17-0.40] versus 0.07 [0.0-0.20] ng/mL; P<0.000) …
Persistence of Zika Virus in Body Fluids - Final Report.
Paz-Bailey G, Rosenberg ES, Doyle K, Munoz-Jordan J, Santiago GA, Klein L, Perez-Padilla J, Medina FA, Waterman SH, Gubern CG, Alvarado LI, Sharp TM. Paz-Bailey G, et al. N Engl J Med. 2017 Feb 14;379(13):1234-1243. doi: 10.1056/NEJMoa1613108. Print 2018 Sep 27. N Engl J Med. 2017. PMID: 28195756 Free PMC article.
A polymorphism in the promoter region of the survivin gene is related to hemorrhagic transformation in patients with acute ischemic stroke.
Mallolas J, Rodríguez R, Gubern C, Camós S, Serena J, Castellanos M. Mallolas J, et al. Neuromolecular Med. 2014 Dec;16(4):856-61. doi: 10.1007/s12017-014-8333-7. Epub 2014 Oct 25. Neuromolecular Med. 2014. PMID: 25344020
The prevalence of the mutant allele (T) was similar in patients and controls (14 vs. 16%, respectively; P = 0.37). However, 9 (29%) patients with allele T had HT compared to 40 (52.6%) of wild-type (P = 0.021). Logistic regression analysis showed that the polymorphi …
The prevalence of the mutant allele (T) was similar in patients and controls (14 vs. 16%, respectively; P = 0.37). However, 9 (29%) p …
[Comparative study of sentinel node biopsy in patients with multifocal breast carcinoma versus in those with unifocal breast carcinoma.].
Solá M, Fraile M, Mariscal A, Julián FJ, Gubern JM, Culell P, Puig P, Peñalva G, Deulofeu P, Janer J, Vallès A, Encinas X, Calvo E, Vallejos V, Milà M. Solá M, et al. Radiologia. 2009 Mar-Apr;51(2):140-7. doi: 10.1016/j.rx.2008.02.005. Epub 2009 Mar 17. Radiologia. 2009. PMID: 19282010 Free article. Spanish.
The mean number of sentinel nodes detected was 1.46, being higher in the MBC group than in the UBC group (1.58 vs 1.45; p=0.036). Extra-axillary sentinel nodes were found in 19.6%; extra-axillary sentinel nodes were more common in the MBC group (23.4% vs 18.9%, ns) and in …
The mean number of sentinel nodes detected was 1.46, being higher in the MBC group than in the UBC group (1.58 vs 1.45; p=0.036). Ext …
18 results