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miR-27a is a master regulator of metabolic reprogramming and chemoresistance in colorectal cancer.
Barisciano G, Colangelo T, Rosato V, Muccillo L, Taddei ML, Ippolito L, Chiarugi P, Galgani M, Bruzzaniti S, Matarese G, Fassan M, Agostini M, Bergamo F, Pucciarelli S, Carbone A, Mazzoccoli G, Colantuoni V, Bianchi F, Sabatino L. Barisciano G, et al. Among authors: chiarugi p. Br J Cancer. 2020 Apr;122(9):1354-1366. doi: 10.1038/s41416-020-0773-2. Epub 2020 Mar 5. Br J Cancer. 2020. PMID: 32132656 Free PMC article.
Insight into the role of low molecular weight phosphotyrosine phosphatase (LMW-PTP) on platelet-derived growth factor receptor (PDGF-r) signaling. LMW-PTP controls PDGF-r kinase activity through TYR-857 dephosphorylation.
Chiarugi P, Cirri P, Taddei ML, Giannoni E, Fiaschi T, Buricchi F, Camici G, Raugei G, Ramponi G. Chiarugi P, et al. J Biol Chem. 2002 Oct 4;277(40):37331-8. doi: 10.1074/jbc.M205203200. Epub 2002 Jul 30. J Biol Chem. 2002. PMID: 12149261 Free article.
LMW-PTP is a positive regulator of tumor onset and growth.
Chiarugi P, Taddei ML, Schiavone N, Papucci L, Giannoni E, Fiaschi T, Capaccioli S, Raugei G, Ramponi G. Chiarugi P, et al. Oncogene. 2004 May 13;23(22):3905-14. doi: 10.1038/sj.onc.1207508. Oncogene. 2004. PMID: 15021900
194 results