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Insulin receptor substrates differentially exacerbate insulin-mediated left ventricular remodeling.
Riehle C, Weatherford ET, Wende AR, Jaishy BP, Seei AW, McCarty NS, Rech M, Shi Q, Reddy GR, Kutschke WJ, Oliveira K, Pires KM, Anderson JC, Diakos NA, Weiss RM, White MF, Drakos SG, Xiang YK, Abel ED. Riehle C, et al. Among authors: kutschke wj. JCI Insight. 2020 Mar 26;5(6):e134920. doi: 10.1172/jci.insight.134920. JCI Insight. 2020. PMID: 32213702 Free PMC article.
A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation.
Erickson JR, Joiner ML, Guan X, Kutschke W, Yang J, Oddis CV, Bartlett RK, Lowe JS, O'Donnell SE, Aykin-Burns N, Zimmerman MC, Zimmerman K, Ham AJ, Weiss RM, Spitz DR, Shea MA, Colbran RJ, Mohler PJ, Anderson ME. Erickson JR, et al. Cell. 2008 May 2;133(3):462-74. doi: 10.1016/j.cell.2008.02.048. Cell. 2008. PMID: 18455987 Free PMC article.
Oxidized CaMKII causes cardiac sinus node dysfunction in mice.
Swaminathan PD, Purohit A, Soni S, Voigt N, Singh MV, Glukhov AV, Gao Z, He BJ, Luczak ED, Joiner ML, Kutschke W, Yang J, Donahue JK, Weiss RM, Grumbach IM, Ogawa M, Chen PS, Efimov I, Dobrev D, Mohler PJ, Hund TJ, Anderson ME. Swaminathan PD, et al. J Clin Invest. 2011 Aug;121(8):3277-88. doi: 10.1172/JCI57833. Epub 2011 Jul 25. J Clin Invest. 2011. PMID: 21785215 Free PMC article.
Oxidation of CaMKII determines the cardiotoxic effects of aldosterone.
He BJ, Joiner ML, Singh MV, Luczak ED, Swaminathan PD, Koval OM, Kutschke W, Allamargot C, Yang J, Guan X, Zimmerman K, Grumbach IM, Weiss RM, Spitz DR, Sigmund CD, Blankesteijn WM, Heymans S, Mohler PJ, Anderson ME. He BJ, et al. Nat Med. 2011 Nov 13;17(12):1610-8. doi: 10.1038/nm.2506. Nat Med. 2011. PMID: 22081025 Free PMC article.
45 results