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Treatment of Cystic Fibrosis Patients Homozygous for F508del with Lumacaftor-Ivacaftor (Orkambi®) Restores Defective CFTR Channel Function in Circulating Mononuclear Cells.
Favia M, Gallo C, Guerra L, De Venuto D, Diana A, Polizzi AM, Montemurro P, Mariggiò MA, Leonetti G, Manca A, Casavola V, Conese M. Favia M, et al. Among authors: conese m. Int J Mol Sci. 2020 Mar 31;21(7):2398. doi: 10.3390/ijms21072398. Int J Mol Sci. 2020. PMID: 32244302 Free PMC article.
Na+/H+ exchanger regulatory factor isoform 1 overexpression modulates cystic fibrosis transmembrane conductance regulator (CFTR) expression and activity in human airway 16HBE14o- cells and rescues DeltaF508 CFTR functional expression in cystic fibrosis cells.
Guerra L, Fanelli T, Favia M, Riccardi SM, Busco G, Cardone RA, Carrabino S, Weinman EJ, Reshkin SJ, Conese M, Casavola V. Guerra L, et al. Among authors: conese m. J Biol Chem. 2005 Dec 9;280(49):40925-33. doi: 10.1074/jbc.M505103200. Epub 2005 Oct 3. J Biol Chem. 2005. PMID: 16203733 Free article.
163 results