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Therapeutic prime/pull vaccination of HSV-2-infected guinea pigs with the ribonucleotide reductase 2 (RR2) protein and CXCL11 chemokine boosts antiviral local tissue-resident and effector memory CD4+ and CD8+ T cells and protects against recurrent genital herpes.
Quadiri A, Prakash S, Dhanushkodi NR, Singer M, Zayou L, Shaik AM, Sun M, Suzer B, Lau LSL, Chilukurri A, Vahed H, Schaefer H, BenMohamed L. Quadiri A, et al. Among authors: shaik am. J Virol. 2024 May 14;98(5):e0159623. doi: 10.1128/jvi.01596-23. Epub 2024 Apr 8. J Virol. 2024. PMID: 38587378
Cross-protection induced by highly conserved human B, CD4+, and CD8+ T-cell epitopes-based vaccine against severe infection, disease, and death caused by multiple SARS-CoV-2 variants of concern.
Prakash S, Dhanushkodi NR, Zayou L, Ibraim IC, Quadiri A, Coulon PG, Tifrea DF, Suzer B, Shaik AM, Chilukuri A, Edwards RA, Singer M, Vahed H, Nesburn AB, Kuppermann BD, Ulmer JB, Gil D, Jones TM, BenMohamed L. Prakash S, et al. Among authors: shaik am. Front Immunol. 2024 Jan 22;15:1328905. doi: 10.3389/fimmu.2024.1328905. eCollection 2024. Front Immunol. 2024. PMID: 38318166 Free PMC article.
Antiviral and Anti-Inflammatory Therapeutic Effect of RAGE-Ig Protein against Multiple SARS-CoV-2 Variants of Concern Demonstrated in K18-hACE2 Mouse and Syrian Golden Hamster Models.
Dhanushkodi NR, Prakash S, Quadiri A, Zayou L, Srivastava R, Shaik AM, Suzer B, Ibraim IC, Landucci G, Tifrea DF, Singer M, Jamal L, Edwards RA, Vahed H, Brown L, BenMohamed L. Dhanushkodi NR, et al. Among authors: shaik am. J Immunol. 2024 Feb 15;212(4):576-585. doi: 10.4049/jimmunol.2300392. J Immunol. 2024. PMID: 38180084
A multi-epitope/CXCL11 prime/pull coronavirus mucosal vaccine boosts the frequency and the function of lung-resident memory CD4+ and CD8+ T cells and enhanced protection against COVID-19-like symptoms and death caused by SARS-CoV-2 infection.
Zayou L, Prakash S, Dhanushkodi NR, Quadiri A, Ibraim IC, Singer M, Salem A, Shaik AM, Suzer B, Chilukuri A, Tran J, Nguyen PC, Sun M, Hormi-Carver KK, Belmouden A, Vahed H, Gil D, Ulmer JB, BenMohamed L. Zayou L, et al. Among authors: shaik am. J Virol. 2023 Dec 21;97(12):e0109623. doi: 10.1128/jvi.01096-23. Epub 2023 Dec 1. J Virol. 2023. PMID: 38038432 Free PMC article.
Therapeutic Prime/Pull Vaccination of HSV-2 Infected Guinea Pigs with the Ribonucleotide Reductase 2 (RR2) Protein and CXCL11 Chemokine Boosts Antiviral Local Tissue-Resident and Effector Memory CD4+ and CD8+ T Cells and Protects Against Recurrent Genital Herpes.
Quadiri A, Prakash S, Dhanushkodi NR, Singer M, Zayou L, Shaik AM, Sun M, Suzer B, Lau L, Chilukurri A, Vahed H, Schaefer H, BenMohamed L. Quadiri A, et al. Among authors: shaik am. bioRxiv [Preprint]. 2023 Aug 9:2023.08.08.552454. doi: 10.1101/2023.08.08.552454. bioRxiv. 2023. PMID: 37609157 Free PMC article. Updated. Preprint.
Mucosal CCL28 Chemokine Improves Protection against Genital Herpes through Mobilization of Antiviral Effector Memory CCR10+CD44+ CD62L-CD8+ T Cells and Memory CCR10+B220+CD27+ B Cells into the Infected Vaginal Mucosa.
Dhanushkodi NR, Prakash S, Quadiri A, Zayou L, Srivastava R, Tran J, Dang V, Shaik AM, Chilukurri A, Suzer B, Vera P, Sun M, Nguyen P, Lee A, Salem A, Loi J, Singer M, Nakayama T, Vahed H, Nesburn AB, BenMohamed L. Dhanushkodi NR, et al. Among authors: shaik am. J Immunol. 2023 Jul 1;211(1):118-129. doi: 10.4049/jimmunol.2300093. J Immunol. 2023. PMID: 37222480
12 results