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Selective delivery of T22-PE24-H6 to CXCR4+ diffuse large B-cell lymphoma cells leads to wide therapeutic index in a disseminated mouse model.
Falgàs A, Pallarès V, Serna N, Sánchez-García L, Sierra J, Gallardo A, Alba-Castellón L, Álamo P, Unzueta U, Villaverde A, Vázquez E, Mangues R, Casanova I. Falgàs A, et al. Theranostics. 2020 Apr 6;10(12):5169-5180. doi: 10.7150/thno.43231. eCollection 2020. Theranostics. 2020. PMID: 32373205 Free PMC article.
A refined cocktailing of pro-apoptotic nanoparticles boosts anti-tumor activity.
Sánchez-García L, Sala R, Serna N, Álamo P, Parladé E, Alba-Castellón L, Voltà-Durán E, Sánchez-Chardi A, Unzueta U, Vázquez E, Mangues R, Villaverde A. Sánchez-García L, et al. Acta Biomater. 2020 Sep 1;113:584-596. doi: 10.1016/j.actbio.2020.06.033. Epub 2020 Jun 27. Acta Biomater. 2020. PMID: 32603867
Rational engineering of a human GFP-like protein scaffold for humanized targeted nanomedicines.
Álamo P, Cedano J, Conchillo-Sole O, Cano-Garrido O, Alba-Castellon L, Serna N, Aviñó A, Carrasco-Diaz LM, Sánchez-Chardi A, Martinez-Torró C, Gallardo A, Cano M, Eritja R, Villaverde A, Mangues R, Vazquez E, Unzueta U. Álamo P, et al. Acta Biomater. 2021 Aug;130:211-222. doi: 10.1016/j.actbio.2021.06.001. Epub 2021 Jun 9. Acta Biomater. 2021. PMID: 34116228
A multivalent Ara-C-prodrug nanoconjugate achieves selective ablation of leukemic cells in an acute myeloid leukemia mouse model.
Pallarès V, Unzueta U, Falgàs A, Aviñó A, Núñez Y, García-León A, Sánchez-García L, Serna N, Gallardo A, Alba-Castellón L, Álamo P, Sierra J, Cedó L, Eritja R, Villaverde A, Vázquez E, Casanova I, Mangues R. Pallarès V, et al. Biomaterials. 2022 Jan;280:121258. doi: 10.1016/j.biomaterials.2021.121258. Epub 2021 Nov 24. Biomaterials. 2022. PMID: 34847435 Free article.
CXCR4-targeted nanotoxins induce GSDME-dependent pyroptosis in head and neck squamous cell carcinoma.
Rioja-Blanco E, Arroyo-Solera I, Álamo P, Casanova I, Gallardo A, Unzueta U, Serna N, Sánchez-García L, Quer M, Villaverde A, Vázquez E, León X, Alba-Castellón L, Mangues R. Rioja-Blanco E, et al. Among authors: alba castellon l. J Exp Clin Cancer Res. 2022 Feb 4;41(1):49. doi: 10.1186/s13046-022-02267-8. J Exp Clin Cancer Res. 2022. PMID: 35120582 Free PMC article.
A diphtheria toxin-based nanoparticle achieves specific cytotoxic effect on CXCR4+ lymphoma cells without toxicity in immunocompromised and immunocompetent mice.
Falgàs A, Garcia-León A, Núñez Y, Serna N, Sánchez-Garcia L, Unzueta U, Voltà-Durán E, Aragó M, Álamo P, Alba-Castellón L, Sierra J, Gallardo A, Villaverde A, Vázquez E, Mangues R, Casanova I. Falgàs A, et al. Among authors: alba castellon l. Biomed Pharmacother. 2022 Jun;150:112940. doi: 10.1016/j.biopha.2022.112940. Epub 2022 Apr 11. Biomed Pharmacother. 2022. PMID: 35421785 Free article.
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