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Discovery and Development of S6821 and S7958 as Potent TAS2R8 Antagonists.
J Med Chem. 2020 May 14;63(9):4957-4977. doi: 10.1021/acs.jmedchem.0c00388. Epub 2020 Apr 24.
J Med Chem. 2020.
PMID: 32330040
Toxicological evaluation of the flavour ingredient N-(1-((4-amino-2,2-dioxido-1H-benzo[c][1,2,6]thiadiazin-5-yl)oxy)-2-methylpropan-2-yl)-2,6-dimethylisonicotinamide (S2218).
Karanewsky DS, Servant G, Liu H, Chi B, Ida L, Saganich M, Werner S, Fotsing JR, Patron A, Tachdjian C, Arthur A.
Karanewsky DS, et al. Among authors: fotsing jr.
Toxicol Rep. 2017 Sep 14;4:507-520. doi: 10.1016/j.toxrep.2017.09.004. eCollection 2017.
Toxicol Rep. 2017.
PMID: 28959681
Free PMC article.
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Inhibitors of VIM-2 by screening pharmacologically active and click-chemistry compound libraries.
Minond D, Saldanha SA, Subramaniam P, Spaargaren M, Spicer T, Fotsing JR, Weide T, Fokin VV, Sharpless KB, Galleni M, Bebrone C, Lassaux P, Hodder P.
Minond D, et al. Among authors: fotsing jr.
Bioorg Med Chem. 2009 Jul 15;17(14):5027-37. doi: 10.1016/j.bmc.2009.05.070. Epub 2009 Jun 22.
Bioorg Med Chem. 2009.
PMID: 19553129
Free PMC article.
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Synthesis of selective agonists for the α7 nicotinic acetylcholine receptor with in situ click-chemistry on acetylcholine-binding protein templates.
Yamauchi JG, Gomez K, Grimster N, Dufouil M, Nemecz A, Fotsing JR, Ho KY, Talley TT, Sharpless KB, Fokin VV, Taylor P.
Yamauchi JG, et al. Among authors: fotsing jr.
Mol Pharmacol. 2012 Oct;82(4):687-99. doi: 10.1124/mol.112.080291. Epub 2012 Jul 11.
Mol Pharmacol. 2012.
PMID: 22784805
Free PMC article.
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NH-1,2,3-Triazole-based Inhibitors of the VIM-2 Metallo-β-Lactamase: Synthesis and Structure-Activity Studies.
Weide T, Saldanha SA, Minond D, Spicer TP, Fotsing JR, Spaargaren M, Frère JM, Bebrone C, Sharpless KB, Hodder PS, Fokin VV.
Weide T, et al. Among authors: fotsing jr.
ACS Med Chem Lett. 2010 Jul 8;1(4):150-154. doi: 10.1021/ml900022q.
ACS Med Chem Lett. 2010.
PMID: 20625539
Free PMC article.
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Generation of candidate ligands for nicotinic acetylcholine receptors via in situ click chemistry with a soluble acetylcholine binding protein template.
Grimster NP, Stump B, Fotsing JR, Weide T, Talley TT, Yamauchi JG, Nemecz Á, Kim C, Ho KY, Sharpless KB, Taylor P, Fokin VV.
Grimster NP, et al. Among authors: fotsing jr.
J Am Chem Soc. 2012 Apr 18;134(15):6732-40. doi: 10.1021/ja3001858. Epub 2012 Apr 6.
J Am Chem Soc. 2012.
PMID: 22394239
Free PMC article.
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Transition-metal-free catalytic synthesis of 1,5-diaryl-1,2,3-triazoles.
Kwok SW, Fotsing JR, Fraser RJ, Rodionov VO, Fokin VV.
Kwok SW, et al. Among authors: fotsing jr.
Org Lett. 2010 Oct 1;12(19):4217-9. doi: 10.1021/ol101568d.
Org Lett. 2010.
PMID: 20825167
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